Application of Xinshenkangning capsule combined with Lisinopril in the treatment of hypertensive nephropathy
Objective:To investigate the curative effect of Xinshenkangning capsule combined with lisinopril on hypertensive nephropathy.Methods:102 patients with hypertensive nephropathy admitted to our hospital from April 2018 to September 2019 were selected as the study objects.The group was divided into control group and observation group with 51 cases in each group.The control group was treated with lisinopril,and the observation group was treated with lisinopril combined with Xinshenkangning capsule.TCM syndrome score,blood pressure level,renal function and occurrence of adverse reactions were analyzed and compared between the two groups.Results:After 2 months of treatment,TCM syndrome score,systolic blood pressure and diastolic blood pressure in observation group were significantly lower than those in control group(P<0.05);Serum creatinine(SCr),blood urea nitrogen(BUN),urinary microalbumin and cystatin C levels in observation group were significantly lower than those in control group(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion:Xinshenkangning capsule combined with lisinopril has a significant effect in the treatment of hypertensive nephropathy,which can reduce the TCM syndrome score and blood pressure of patients,improve renal function,and has high safety.
Hypertensive nephropathyXinshenkangning capsuleLisinoprilBlood PressureRenal function
万方数据
维普
