Correlation between serum PCT and CRP levels and the therapeutic effect of ambroxol hydrochloride on neonatal pneumonia
Objective:To analyze the relationship between serum procalcitonin(PCT)and C-reactive protein(CRP)and the therapeutic effect of ambroxol hydrochloride on neonatal pneumonia(NP).Methods:150 children with NP admitted to our hospital from July 2019 to April 2021 were selected as the study objects.All the children were treated with ambroxol hydrochloride after admission,and the clinical efficacy was observed and recorded for 7 days.According to the different therapeutic effects,the children were divided into effective group and ineffective group.The baseline data and the levels of serum PCT and CRP at admission were analyzed,and the relationship between the levels of serum PCT and CRP at admission and the therapeutic effect of ambroxol hydrochloride in children with NP was analyzed.Results:After 7 days of treatment,21 cases(14.00%)of 150 cases were ineffective.The levels of serum PCT and CRP in the ineffective group were higher than those in the effective group,and the difference was statistically significant(P<0.05).Logistic regression analysis showed that the high expression of serum PCT and CRP was associated with the ineffective treatment of ambroxol hydrochloride in children with NP(OR>1,P<0.05).Conclusion:The high expression of serum PCT and CRP is associated with the ineffective treatment of ambroxol hydrochloride in children with NP.
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