Effect of metoprolol assisted with amiodarone on patients with coronary heart disease complicated with ventricular arrhythmia and B-type natriuretic peptide
Objective:To investigate the clinical efficacy of metoprolol assisted with amiodarone in the treatment of coronary heart disease complicated with ventricular arrhythmia and its effect on B-type natriuretic peptide.Methods:From May 2022 to May 2023,88 patients with coronary heart disease combined with ventricular arrhythmia were selected from the cardiology department of our hospital.The patients were randomly divided into control group and study group,44 cases in each group.The control group received amiodarone treatment;The study group was treated with metoprolol adjuvant amiodarone.After 7 days of treatment,the clinical efficacy,cardiac function,arrhythmia onset and B-type natriuretic peptide levels of the two groups were analyzed and compared.Results:Compared with the control group,the total effective rate of the study group was significantly higher than that of the control group(P<0.05).After treatment,the levels of cardiac function indexes such as cardiac output volume,stroke output and left ventricular ejection fraction in the study group were significantly higher than those in the control group(P<0.05).The arrhythmia attack frequency and B-type natriuretic peptide level in the study group were significantly lower than those in the control group,and the single attack duration of arrhythmia was significantly shorter than that in the control group(P<0.05).Conclusion:Metoprolol assisted with amiodarone in the treatment of coronary heart disease complicated with ventricular arrhythmia has significant clinical efficacy,which can not only significantly improve the cardiac function and arrhythmia,but also significantly reduce the level of B-type natriuretic peptide.
Coronary heart diseaseVentricular arrhythmiaMetoprololAmiodaroneCurative effectB type natriuretic peptide
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维普
