首页|不同浓度的曲安奈德联合瘢痕疙瘩切除术在瘢痕疙瘩治疗中的效果研究

不同浓度的曲安奈德联合瘢痕疙瘩切除术在瘢痕疙瘩治疗中的效果研究

扫码查看
目的:分析不同浓度的曲安奈德联合瘢痕疙瘩切除术治疗瘢痕疙瘩的临床疗效.方法:回顾性分析 2020 年3 月至 2023 年 5 月期间本院收治的 94 例瘢痕疙瘩行瘢痕疙瘩切除术患者的临床资料,根据采用的曲安奈德浓度的不同将患者分为低浓度组(n=44)和高浓度组(n=50).分析比较治疗 3 m后临床疗效和治疗后 1 y复发率;采用温哥华瘢痕量表(Vancouver Scar Scale,VSS)评估瘢痕恢复情况;采用焦虑自评量表(Self-rating anxiety scale,SAS)以及抑郁自评量表(Self-rating depression scale,SDS)评估心理状态;同时观察不良反应发生情况.结果:高浓度组的治疗总疗效率显著高于低浓度组(P<0.05).治疗后,两组患者VSS、SAS及SDS评分均显著下降,且高浓度组的VSS、SAS及SDS评分显著低于低浓度组(P<0.05).两组不良反应发生率及治疗后 1 y复发率无显著差异(P>0.05).结论:高低浓度曲安奈德联合瘢痕疙瘩切除术治疗瘢痕疙瘩临床疗效更佳,更有利改善患者心理状态,术后恢复更好.
Effect of triamcinolone and keloidectomy with different concentrations in treating keloid
Objective:To analyze the clinical efficacy of different concentrations of triamcinolone acetonide combined with keloidectomy in treating keloid.Method:A retrospective analysis was conducted on the clinical data of 94 patients with keloid who underwent keloidectomy at our hospital from March 2020 to May 2023.The patients were divided into a low-concentration group(n=44)and a high-concentration group(n=50)based on the concentration of triamcinolone acetonide used during treatment.Analyze and compare the clinical efficacy after 3 months of treatment and the recurrence rate after 1 year.The recovery of scars was evaluated using the Vancouver Scar Scale(VSS).The psychological state was evaluated using the Self-rating anxiety scale(SAS)and the Self-rating depression scale(SDS).At the same time,the occurrence of adverse reactions was observed.Results:The total treatment efficiency of the high-concentration group was significantly higher than that of the low-concentration group(P<0.05).After treatment,the VSS,SAS,and SDS scores in both groups decreased significantly,and the VSS,SAS,and SDS scores in the high-concentration group were lower than those in the low-concentration group(P<0.05).There was no significant difference in the incidence of adverse reactions and recurrence rate 1 year after treatment between the two groups(P>0.05).Conclusion:The clinical efficacy of high and low concentrations of triamcinolone acetonide combined with keloid resection in treating keloid is better,which is more conducive to improving the patient's psychological state and achieving better postoperative recovery.

Different concentrationTriamcinoloneKeloidKeloidectomyTherapeutic effect

张超、何楠楠、陈静

展开 >

开封一五五医院皮肤科,河南 开封 475000

不同浓度 曲安奈德 瘢痕疙瘩 瘢痕疙瘩切除术 治疗效果

2024

四川生理科学杂志
四川省生理科学会

四川生理科学杂志

影响因子:0.575
ISSN:1671-3885
年,卷(期):2024.46(10)