Study on the correlation between cerebral edema status and bleeding volume in patients with cerebral hemorrhage
Objective:To investigate the correlation between the duration of peak cerebral edema and the amount of bleeding in patients with cerebral hemorrhage.Methods:From January 2021 to December 2023,80 patients with cerebral hemorrhage diagnosed and treated in the Department of Neurology,intensive care Medicine and neurosurgery of our hospital were selected as the research objects.Cerebral edema and bleeding volume of the patients were detected at admission,6 hours after admission,12 hours after admission,24 hours after admission,48 hours after admission and after admission.The duration of the peak period of cerebral edema was recorded according to the volume of cerebral edema.The correlation between the peak duration of cerebral edema and the amount of bleeding in patients with cerebral hemorrhage was tested by bivariate Pearson correlation analysis,and the effect of the amount of bleeding on the peak duration of cerebral edema in patients with cerebral hemorrhage was analyzed.Results:The volume of cerebral edema at 6h and 12h after admission of 80 patients with cerebral hemorrhage had no significant change compared with that at admission,and began to increase at 24h after admission,reached a peak at 48h after admission,and continued to maintain a high level until 10d after admission,the overall difference of cerebral edema volume at each time point was statistically significant(P<0.05).The average volume of basal ganglia bleeding in 80 patients with cerebral hemorrhage was 25.14±7.23 mL.With the bleeding amount of 20mL as the boundary,the patients were divided into the bleeding amount>20mL group,≤20mL group,and the duration of cerebral edema in the>20mL group was longer than that in the≤20mL group,and the difference was statistically significant(P<0.05).Bivariate Pearson correlation test showed that the duration of cerebral edema in patients with cerebral hemorrhage was positively correlated with the amount of blood loss(r=0.967,P<0.001).Linear regression analysis showed that increased cerebral hemorrhage was a risk factor for prolonged duration of peak cerebral edema(β=3.480,95%CI:1.285-5.675,t=3.156,P=0.002).Conclusion:The duration of cerebral edema in patients with cerebral hemorrhage is positively correlated with the amount of blood loss,and the increase of blood loss may be a risk factor for the prolonged duration of the peak value of cerebral edema.
Cerebral hemorrhageCerebral edemaPeak periodDurationAmount of blood lossCorrelation
万方数据
维普
