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肺叶切除术与肺楔形切除术治疗ⅠA期NSCLC的疗效分析

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目的:对比肺叶切除术与肺楔形切除术对ⅠA期非小细胞肺癌(Non-small cell lung cancer,NSCLC)的疗效情况.方法:回顾性收集2021年6月至2023年1月期间于本院行肺叶切除术或肺楔形切除术的75例ⅠA期NSCLC患者的临床资料,根据手术方式的不同分为观察组(肺楔形切除术,n=44)与对照组(肺叶切除术,n=31).采用回顾性方法收集两组患者的临床资料,包括手术时间、术中出血量、术后疼痛程度、住院时间、住院期间并发症发生情况、术后 3 m生活质量以及术后 1 y生存质量,并对资料进行统计分析,对比两组的临床疗效.结果:观察组的手术时间、术中出血量、术后疼痛程度、住院时间均比对照组显著降低(P<0.05),但两组的置管时间无显著差异(P>0.05).两组住院期间的术后并发症发生率无显著差异(P>0.05).术后3 y,观察组患者的生活质量评分较对照组更高,差异具有统计学意义(P<0.05).两组的术后一年复发率、远处转移发生率、死亡率均无显著差异(P>0.05).结论:相比于肺叶切除术,肺楔形切除术能改善ⅠA期NSCLC患者手术情况,有利于促进患者术后恢复和提高生活质量.
Analysis of the efficacy of lobectomy and wedge resection in the treatment of stage IA NSCLC
Objective:To compare the efficacy of lobectomy and wedge resection for stage ⅠA non-small cell lung cancer(NSCLC).Methods:The clinical data of 75 patients with stage IA NSCLC who underwent lobectomy or wedge resection in our hospital from June 2021 to January 2023 were retrospectively collected.The patients were divided into an observation group(n=44)and a control group(n=31)according to the surgical procedure.Retrospective methods were used to collect clinical data from the two groups of patients,including operation time,intraoperative blood loss,postoperative pain level,length of hospital stay,complications during hospitalization,quality of life at 3 months after surgery,and quality of life at 1 year after surgery.The data were statistically analyzed to compare the clinical efficacy of the two groups.Results:The operation time,intraoperative blood loss,postoperative pain level,and hospitalization time in the observation group were significantly lower than those in the control group(P<0.05),but there was no significant difference in the catheterization time between the two groups(P>0.05).There was no significant difference in the incidence of postoperative complications between the two groups during hospitalization(P>0.05).At 3 years after surgery,the quality of life score of patients in the observation group was higher than that of the control group,and the difference was statistically significant(P<0.05).There were no significant differences in the recurrence rate,distant metastasis rate,and mortality rate between the two groups one year after surgery(P>0.05).Conclusion:Compared with lobectomy,wedge resection can improve the surgical condition of patients with stage IA NSCLC,which promotes postoperative recovery and enhances quality of life.

Pulmonary lobectomyPulmonary cuneiform resectionStage ⅠA NSCLCCurative effect

闫国旗、杜浩朋

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安阳市人民医院胸外科,河南 安阳 455000

肺叶切除术 肺楔形切除术 ⅠA期NSCLC 疗效

2024

四川生理科学杂志
四川省生理科学会

四川生理科学杂志

影响因子:0.575
ISSN:1671-3885
年,卷(期):2024.46(10)