Effect analysis of Tiandan Tongluo tablets combined with Defibrase injection in the treatment of acute cerebral infarction
Objective:To explore the effect of Tiandan Tongluo Tablet combined with Defibrase(Df)injection in the treatment of acute cerebral infarction(ACI).Methods:The case data of 64 patients with ACI in our hospital from January 2021 to April 2024 were retrospectively collected and divided into two groups according to different medication regimens.The 32 patients received Df injection were listed as the single treatment group.The 32 patients received the treatment of Tian-Dan-Tong-Luo Tablet combined with Df injection were listed as the combined treatment group,and the efficacy,the National Institute of Health Stroke Scale(NIHSS),Montreal Cognitive Assessment(MoCA)scores,cerebral hemodynamic parameters[characteristic impedance(ZCV),mean cerebrovascular blood flow(Qmean),dynamic resistance(DR),mean flow velocity(Vmean)],serum indexes and adverse reaction rates of the two groups were compared.Results:The total effective rate of the combined treatment group was much higher than that of single treatment group(P<0.05).Compared with the single treatment group,after treatment,the combined treatment group had lower NIHSS score,levels of ZCV,DR,and serum indexes levels,higher MoCA score,levels of Qmean and Vmean(P<0.05);There was no significant difference in the incidence of adverse reactions between the two groups.Conclusion:Tiandan Tongluo tablets combined with Df injection in the treatment of ACI patients is not only safe,but also can further improve the curative effect,neurological and cognitive function,regulate the level of cerebral hemodynamics,and improve the level of cytokines.
NETL
NSTL
万方数据
