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肠镜在结直肠息肉切除术后复发监测中的应用

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目的:探讨肠镜在结直肠息肉切除术后复发监测中的应用.方法:选取 2021 年 10 月-2023 年6 月期间于本院接受结直肠息肉切除术的患者 112 例为研究对象.术后随访 5 y,1 y内复查一次肠镜、CT结肠成像检查.以病理检查为"金标准",分析所有患者息肉复发情况,对比肠镜、CT在结直肠息肉切除术后复发监测中的准确性.评估肠镜、CT监测术后复发结果与金标准检查结果的一致性.采用Logistic回归模型分析影响结直肠息肉切除术后复发的危险因素.结果:病理检查发现患者 5 y内复发率高达 73.21%(82/112).中位复发时间为 1.4 y,在术后不同时间段内复发率研究结果显示:1 y内复发率为 35.71%(40/112),至第 2 y时上升至 56.25%(63/112),到第3 y 时为 66.96%(75/112),至第 4 y 进一步增加至 71.43%(80/112),而到第 5 y,复发率基本稳定在 73.21%(82/112).以病理检查为"金标准",112 例患者中,肠镜5 y内检出息肉复发率为 70.53%(79/112),其中肠镜对息肉复发的准确性为 96.34%(79/82);CT 5 y内检出息肉复发率为 57.14%(64/112),其中CT对息肉复发的检出准确性为 78.05%(64/82),肠镜 5 y内检出息肉的准确性明显高于CT 5 y内检出息肉的检出准确性,差异有统计学意义(χ2=4.351,P<0.05).肠镜、CT监测术后复发结果与金标准检查结果的一致性Kappa值分别为 0.631、0.819.结直肠息肉是否复发设为因变量,并以患者临床资料作为自变量,通过Logistic多因素分析结果显示:年龄≥60 岁、肠息肉≥3 个、肠息肉直径≥2 cm均为影响结直肠息肉切除术后复发的危险因素(P<0.05).结论:肠镜在结直肠息肉切除术后复发监测中具有重要意义,可为临床医生提供有力的依据,及时发现和处理复发息肉,降低结直肠癌发生率,提高治疗成功率和生活质量.
Application of colonoscopy in monitoring recurrence of colorectal polyps after resection
Objective:To investigate the application of colonoscopy in monitoring the recurrence of colorectal polyps after resection.Methods:112 patients who underwent colorectal polyp resection in our hospital from October 2021 to June 2023 were selected as the study objects.Postoperative follow-up was 5 years,and colonoscopy and CT colon imaging were reviewed within 1 year.Pathological examination was used as the"gold standard"to analyze the recurrence of polyps in all patients and compare the accuracy of colonoscopy and CT in monitoring the recurrence of colorectal polyps after resection.To evaluate the consistency between the results of postoperative recurrence monitored by colonoscopy and CT and the results of gold standard.Logistic regression model was used to analyze the risk factors of recurrence after colorectal polyp resection.Results:The recurrence rate within 5 years was 73.21%(82/112).The median time to recurrence was 1.4 years,and the results of the recurrence rate study in different time periods after surgery showed that:The recurrence rate was 35.71%(40/112)in 1 year,increased to 56.25%(63/112)in 2 years,66.96%(75/112)in 3 years,further increased to 71.43%(80/112)in 4 years,and basically stabilized at 73.21%(82/112)in 5 years.Taking pathological examination as the"gold standard",the recurrence rate of polyps detected by colonoscopy within 5 years was 70.53%(79/112)in 112 patients,and the accuracy of colonoscopy for polyp recurrence was 96.34%(79/82).The recurrence rate of polyps detected within CT 5 years was 57.14%(64/112),and the accuracy of CT in detecting polyps recurrence within 5 years was 78.05%(64/82),and the accuracy of colonoscopy in detecting polyps within 5 years was significantly higher than that of CT 5 years,with statistical significance(χ2=4.351,P<0.05).The results of postoperative recurrence monitored by colonoscopy and CT were 0.631 and 0.819,respectively.The recurrence of colorectal polyps was set as the dependent variable,and clinical data of the patient was taken as the independent variable.Logistic multivariate analysis showed that age≥60 years,≥3 intestinal polyps,and diameter of intestinal polyps≥2 cm were all risk factors for recurrence after colorectal polyp resection(P<0.05).Conclusion:Colonoscopy is of great significance in monitoring the recurrence of colorectal polyps after resection,which can provide a strong basis for clinicians to detect and treat recurrent polyps in time,reduce the incidence of colorectal cancer,improve the success rate of treatment and quality of life.

EnteroscopyColorectalColorectal polypectomyPolyp recurrence

李阳子、朱琳、李玉玲

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南阳医学高等专科学校第一附属医院消化内科,河南 南阳 473000

肠镜 结直肠 结直肠息肉切除术 息肉复发

2024

四川生理科学杂志
四川省生理科学会

四川生理科学杂志

影响因子:0.575
ISSN:1671-3885
年,卷(期):2024.46(12)