Effect of pneumoperitoneum pressure on postoperative recovery,intestinal function,and liver function in patients undergoing laparoscopic cholecystectomy for gallstones
Objective:To investigate the effect of pneumoperitoneum pressure on postoperative recovery,intestinal function,and liver function in patients undergoing laparoscopic cholecystectomy for gallstones.Methods:Using the random number table method,60 patients who underwent laparoscopic cholecystectomy in the hospital from January 2021 to January 2024 were assigned to the high pressure group(pneumoperitoneum pressure of 12-15 mmHg)and the low pressure group(pneumoperitoneum pressure of 8-12 mmHg),with 30 cases in each group.The two groups were compared in terms of surgical indicators,postoperative recovery,intestinal function,liver function,and adverse reactions.Results:There was no significant difference between the groups in terms of surgery time,intraoperative blood loss,duration of pneumoperitoneum,and carbon dioxide(CO2)consumption(P>0.05).Postoperative anal exhaust time,bowel sound recovery time,postoperative bowel movement time,and hospitalization time of the low pressure group were significantly shorter compared with the high pressure group(P<0.05).Compared with preoperative levels,the levels of aspartate aminotransferase(AST)and alanine aminotransferase(ALT)in both groups were significantly higher on day 1 after surgery(P<0.05).Meanwhile,the levels of AST and ALT in the high pressure group were significantly higher(P<0.05).Compared with preoperative levels,there was no significant difference in the levels of AST and ALT in the two groups on day 3 after surgery(P>0.05).The incidence of complications in the low pressure group was significantly lower than that in the high pressure group(P>0.05).Conclusion:Maintaining pneumoperitoneum pressure at 8-12 mmHg during laparoscopic cholecystectomy for patients with gallstones can reduce damage to liver and intestinal function and complications,which is conducive to postoperative recovery.
Pneumoperitoneum pressureGallstoneLaparoscopic cholecystectomyIntestinal functionLiver function
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