首页|探究DCE-MRI参数及表观弥散系数对肝癌微血管侵犯的评估价值

探究DCE-MRI参数及表观弥散系数对肝癌微血管侵犯的评估价值

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目的:探讨动态对比增强磁共振成像(Dynamic Contrast-Enhanced Magnetic Resonance Imaging,DCE-MRI)参数及表观弥散系数(Apparent Diffusion Coefficient,ADC)值评估肝癌微血管侵犯的价值.方法:选取 2021 年2 月至 2023 年4 月经手术治疗的 85 例肝癌患者作为研究对象.患者术前经DCE-MRI检查并测量ADC值.术后病理诊断分析肝癌微血管侵犯结果并将患者分为微血管侵犯阳性组和微血管侵犯阴性组.分析 DCE-MRI 参数及ADC值对肝癌微血管侵犯的评估价值.结果:85 例肝癌患者,术后病理诊断结果显示,33 例患者微血管侵犯呈阳性,52 例患者微血管侵犯呈阴性;微血管侵犯阳性组Ktrans、Kep以及Ve值均高于阴性组,且ADC值低于阴性组(P<0.05);绘制受试者工作特征曲线,结果显示,DCE-MRI扫描所得参数(Ktrans、Kep以及Ve)及ADC值评估肝癌微血管侵犯有一定价值,曲线下面积均>0.70,且以联合评估价值更为理想.结论:肝癌患者术前DCE-MRI参数、ADC值可联合用于评估微血管侵犯情况.
Value of DCE-MRI parameters and apparent diffusion coefficient in evaluating microvascular invasion of hepatocellular carcinoma
Objective:To evaluate the value of dynamic contrast-enhanced magnetic resonance imaging(DCE-MRI)parameters and apparent diffusion coefficient(ADC)values in microvascular invasion of hepatocellular carcinoma.Methods:85 patients with liver cancer who underwent surgical treatment from February 2021 to April 2023 were selected as the study objects.The ADC values were measured by DCE-MRI before operation.The results of microvascular invasion were analyzed and patients were divided into microvascular invasion positive group and microvascular invasion negative group.To analyze the value of DCE-MRI parameters and ADC values in evaluating microvascular invasion of hepatocellular carcinoma.Results:In 85 patients with liver cancer,the pathological diagnosis showed that 33 patients were positive for microvascular invasion,52 patients were negative.Ktrans,Kep and Ve values in positive microvascular invasion group were higher than those in negative group,and ADC values were lower than those in negative group(P<0.05).Receiver operating characteristic curve was drawn.The results showed that the parameters obtained by DCE-MRI scanning(Ktrans,Kep,Ve)and ADC values had certain value in evaluating microvascular invasion of liver cancer,and the area under the curve were all greater than 0.70,and the combined evaluation value was more ideal.Conclusion:Preoperative DCE-MRI parameters and ADC values can be used to evaluate microvascular invasion in patients with liver cancer.

Hepatocellular carcinomaMicrovascular invasionDynamic contrast-enhanced magnetic resonance imagingApparent dispersion coefficient

赵美东

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固始县中医院影像科,河南 信阳 465200

肝癌 微血管侵犯 动态对比增强磁共振成像 表观弥散系数

2024

四川生理科学杂志
四川省生理科学会

四川生理科学杂志

影响因子:0.575
ISSN:1671-3885
年,卷(期):2024.46(12)