Effect of terbutaline sulfate combined with budesonide suspension for inhalation in the treatment of patients with bronchopneumonia and the impact on cytokines and immune function
Objective:To observe the effect of terbutaline sulfate combined with budesonide suspension for inhalation in the treatment of patients with bronchopneumonia,and the impact on cytokines and immune function.Methods:Sixty-four patients with bronchopneumonia treated in the hospital from January 2023 to June 2024 were selected,and divided into a control group(32 cases)and a combination group(32 cases)according to the random number table.The former was treated with budesonide suspension for inhalation,and the latter was treated with terbutaline sulfate on this basis.The two groups were compared in terms of treatment outcomes,the levels of inflammatory factors[C-reactive protein(CRP)and white blood cells(WBC)],immune indicators[T lymphocytes(CD3+and CD4+/CD8+)],and adverse reactions.Results:Compared to control group,the total effective rate of combination group was higher(P<0.05).After treatment,the levels of CRP and WBC in both groups decreased,and the levels were lower in combination group(P<0.05).After treatment,the levels of CD3+and CD4+/CD8+in both groups increased,and the levels were higher in combination group(P<0.05).There were more patients with adverse reactions in the control group,but the difference was not statistically significant(P>0.05).Conclusion:The combined treatment with terbutaline sulfate and budesonide suspension for inhalation is effective for patients with bronchopneumonia.It can lower the levels of inflammatory factors,improve immune function,and is safe.
BronchopneumoniaBudesonide suspension for inhalationTebutaline sulfateInflammatory factorImmune function
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