Correlation of visceral fat index,hemoglobin and thyroid stimulating hormone levels with cardiac autonomic neuropathy in type 2 diabetes mellitus
Objective:To investigate the correlation of visceral fat index,hemoglobin and thyrotropin levels and cardiac autonomic neuropathy(DCAN)in type 2 diabetes mellitus.Methods:118 patients with type 2 diabetes admitted to our hospital from February 2023 to May 2024 were selected as the study objects.Patients were divided into DCAN group(68 cases)and non-DCAN group(50 cases)according to whether developed to DCAN.The clinical data of patients were collected,the differences of visceral fat index,hemoglobin and thyrotropin levels between groups were analyzed,and then the factors affecting the occurrence of DCAN were explored in patients with type 2 diabetes.Results:Visceral fat index and thyroid stimulating hormone level in DCAN group were significantly higher than those in non-DCAN group,and hemoglobin level was significantly lower than that in non-DCAN group(P<0.05).The duration of diabetes in DCAN group was significantly longer than that in non-DCAN group,the proportion of smoking patients was significantly higher than that in non-DCAN group,the levels of glycosylated hemoglobin,fasting blood glucose,total cholesterol,low density lipoprotein cholesterol,urinary microalbumin/creatinine were significantly higher than those in non-DCAN group,and the level of free tetraiodothyronine was significantly lower than that in non-DCAN group(P<0.05).Visceral fat index,hemoglobin,thyrotropin,glycosylated hemoglobin and low density lipoprotein cholesterol were the factors influencing DCAN.The predictive model was established with an AUC value of 0.908(95%CI:0.855-0.962),an optimal cut-off value of 36.126,a sensitivity of 0.809,and a specificity of 0.900.Conclusion:The increased visceral fat index and thyroid stimulating hormone level,and the decreased hemoglobin level increase the risk of DCAN in T2DM patients.The occurrence model of DCAN based on multivariate analysis can effectively predict the occurrence of DCAN.
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