首页|经鼻高流量湿化氧疗对慢阻肺合并慢性左心衰竭患者的作用分析

经鼻高流量湿化氧疗对慢阻肺合并慢性左心衰竭患者的作用分析

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目的:探讨经鼻高流量湿化氧疗对慢性阻塞性肺疾病(COPD)合并慢性左心衰竭患者(HFNC)的治疗效果.方法:回顾性收集 2021 年 1 月至 2023 年 6 月期间本院收治的 98 例COPD合并慢性左心衰竭患者的临床资料.根据治疗方案的不同将患者分为对照组(经鼻导管吸氧治疗,n=49)与观察组(HFNC 治疗,n=49).分析对比两组的呼吸困难指数(mMRC评分)、心功能、血气参数及安全性.结果:治疗后,观察组mMRC评分、NT-proBNP、PaCO2 水平显著低于对照组,LVEF、PaO2 水平显著高于对照组(P<0.05).观察组的不良事件总发生率显著低于对照组(P<0.05).结论:HFNC应用在COPD合并慢性左心衰竭患者的治疗中,能缓解患者的呼吸困难症状,改善心功能指标和血气参数,提高安全性.
Effect of nasal high flow humidified oxygen therapy on patients with chronic obstructive pulmonary disease complicated with chronic left heart failure
Objective:To investigate the effect of nasal high flow humidified oxygen therapy on chronic obstructive pulmonary disease(COPD)complicated with chronic left heart failure(HFNC).Methods:The clinical data of 98 patients with COPD combined with chronic left heart failure admitted to our hospital from January 2021 to June 2023 were retrospectively collected.Patients were divided into control group(nasal catheter oxygen therapy,n=49)and observation group(HFNC treatment,n=49)according to different treatment regiments.The dyspnea index(mMRC score),cardiac function,blood gas parameters and safety were analyzed and compared between the two groups.Results:After treatment,the mMRC score,NT-proBNP and PaCO2 levels in the observation group were significantly lower than those in the control group,and the LVEF and PaO2 levels were significantly higher than those in the control group(P<0.05).The total incidence of adverse events in the observation group was significantly lower than that in the control group(P<0.05).Conclusion:The application of HFNC in the treatment of COPD patients with chronic left heart failure can alleviate dyspnea symptoms,improve cardiac function indexes and blood gas parameters,and improve safety.

Chronic obstructive pulmonary diseaseChronic left heart failureNasal high flow humidified oxygen therapyDyspnea indexCardiac function

王燕、燕鑫鑫、刘晓灿

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淮滨县人民医院重症医学科,河南 信阳 464400

安阳市人民医院 ICU,河南 安阳 455000

淮滨县人民医院ICU,河南 信阳 464400

慢阻肺 慢性左心衰竭 经鼻高流量湿化氧疗 呼吸困难指数 心功能

2024

四川生理科学杂志
四川省生理科学会

四川生理科学杂志

影响因子:0.575
ISSN:1671-3885
年,卷(期):2024.46(12)