肠道菌群昼夜节律与宿主健康研究进展
Advances in circadian rhythm of gut microbiota and host health
王少璞 1曾书秦1
作者信息
- 1. 四川大学华西第二医院儿科/出生缺陷与相关妇儿疾病教育部重点实验室,四川 成都 610041
- 折叠
摘要
肠道菌群是存在于消化道的微生物群落,与机体健康密切相关.肠道细菌昼夜节律最早出现在婴儿出生两周后,并且随着年龄增加,昼夜节律特征而变得愈发显著.肠道菌群受到多种因素的影响,并且菌群失调会引起一系列的疾病发生.基于肠道菌群对人体健康的影响,本文通过探究影响肠道菌群昼夜节律的因素,包括饮食,宿主内在机制等,阐明肠道菌群昼夜节律破坏对宿主健康的影响,为菌群治疗临床疾病提供重要理论依据.
Abstract
The gut microbiota of humans is a community of microorganisms in the digestive tract,which is closely related to the host health.The circadian rhythm of gut microbiota first appears two weeks after birth and becomes more pronounced with age.The gut microbiota is influenced by multiple factors,and its dysbiosis causes a wide range of diseases.Given the impact of gut microbiota on human health,this review explores the factors that affect the circadian rhythm of gut microbiota,including diet and mechanism associated with the host,and clarifies the impact of disruption of circadian rhythm of gut microbiota on human health,providing an important theoretical basis for the treatment of clinical diseases by microbiota.
关键词
肠道菌群/昼夜节律/宿主健康Key words
Gut microbiota/Circadian rhythm/Host health引用本文复制引用
出版年
2024
NETL
NSTL
万方数据