Relationship between TCM syndrome types and the severity of PHG
Objective:To investigate the relationship between different TCM syndrome types and the severity of portal hyper-tensive gastropathy(PHG).Methods:Clinical data of 247patients with PHG diagnosed and treated in the hospital from January 2019to November 2022were reviewed.The patients'baseline data,serum indicators and other general data were collected.All pa-tients received TCM syndrome diagnosis.Disease severity,Child-Pugh grade and clinical indicators in patients with different TCM syndrome types were comparatively analyzed,and correlation analysis was performed.Results:Among the 247patients,there were 52patients with dampness-heat amassment syndrome,45patients with liver qi stagnation syndrome,35patients with liver-kidney yin deficiency syndrome,33patients with water dampness stagnation syndrome,45patients with static blood blocking collaterals syndrome and 37patients with spleen-kidney yang deficiency syndrome.There were statistically significant differences in the con-stituent ratios of different grade of PHG among patients with different TCM syndromes.The proportions of grade 2and grade 3static blood blocking collaterals syndrome were the highest(20.61％and 25.64％).There were statistically significant differences in the constituent ratios of Child-Pugh grades among patients with different TCM syndromes(P＜0.05).The proportions of grade B and grade C dampness-heat amassment syndrome were the highest(20.61％and 25.00％).There were statistically significant differences in fibrinogen,platelet count and high-sensitivity C-reactive protein levels among patients with different TCM syn-dromes(P＜0.05).Referring to liver qi stagnation syndrome,there was a statistically significant difference in the risk of grade 4PHG in patients with static blood blocking collaterals syndrome(P＜0.05).Conclusion:The common TCM syndrome types of PHG include dampness-heat amassment syndrome,liver qi stagnation syndrome,liver-kidney yin deficiency syndrome,water dampness stagnation syndrome,static blood blocking collaterals syndrome and spleen-kidney yang deficiency syndrome.These TCM syndrome types are closely related to the severity of the disease and Child-Pugh grade.Conditions of patients with static blood blocking collaterals syndrome and dampness-heat amassment syndrome are relatively severe,which can be used as an ob-jective basis for treatment based on TCM syndrome differentiation.
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