首页|桑麻二虫汤治疗社区获得性肺炎(风热犯肺证)临床研究

桑麻二虫汤治疗社区获得性肺炎(风热犯肺证)临床研究

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目的:评价桑麻二虫汤治疗社区获得性肺炎(CAP)(风热犯肺证)患者的疗效和安全性.方法:将2021年5月至2021年12月在我院治疗的116例CAP(风热犯肺证)患者随机分为治疗组(58例)和对照组(58例),对照组予以西医常规治疗,观察组在西医治疗基础上予以口服桑麻二虫汤,两组患者疗程均为7天.比较两组患者治疗的总有效率,发热、咳嗽、咯痰中医证候评分及肺部感染评分(CPIS),同时比较两组患者退热时间、咳嗽消失时间和咯痰消失时间,以及降钙素原(PCT)、白细胞计数(WBC)、C反应蛋白(CRP)水平,同时观察记录两组患者不良反应发生情况.结果:观察组患者的治疗总有效率明显高于对照组(P<0.05).治疗后,两组患者的发热、咳嗽、咯痰评分与CPIS评分较治疗前均有降低(P<0.05),且观察组显著低于对照组(P<0.05);观察组患者的退热时间、咳嗽和咯痰消失时间均比对照组明显缩短(P<0.05);两组患者的WBC、CRP、PCT水平较治疗前均降低(P<0.05),且观察组上述指标明显低于对照组(P<0.05).治疗组有1例患者初次口服中药后出现短暂头晕、恶心,测血压正常,休息后自行缓解,对照组无明显不良反应发生.结论:桑麻二虫汤治疗CAP(风热犯肺证)可以提高疗效,缩短病程,降低炎症因子水平,并且无明显不良反应发生.
Observation on the Therapeutic Effect of Sangma Erchong decoction on Community Acquired Pneumonia Patients with syndrome of wind-heat invading lung
Sichuan Integrative Medicine Hospital(Chengdu 610041,Sichuan)Abstract:Objective:To evaluate the effi-cacy and safety of Sangma Erchong decoction in the treatment of community-acquired pneumonia(CAP)patients with syndrome of wind-heat invading lung.Method:A total of 116patients with CAP(lung syndrome caused by wind and heat)treated in our hospital from May 2021to December 2021were divided into the treatment group(58cases)and the control group(58cases)ac-cording to the random number table method.The control group was given conventional western medicine treatment,and the obser-vation group was treated with Sanma Erzhi decoction on the basis of western medicine treatment.The total effective rate,tradition-al Chinese medicine symptom scores of fever,cough,expectoration and pulmonary infection score(CPIS)were compared be-tween the two groups.The antipyretic time,cough disappearance time and expectoration disappearance time,procalcitonin(PCT),white blood cell count(WBC)and C-reactive protein(CRP)levels were compared between the two groups.Mean-while,the adverse reactions of the two groups were observed and recorded.Results:The total effective rate of the observation group was significantly higher than the control group(P<0.05).After treatment,the scores of fever,cough,expectoration and CPIS in the two groups were lower than those before treatment(P<0.05),and those in the observation group were significantly lower than those in the control group(P<0.05).The antipyretic time,cough and expectoration disappearance time of the observa-tion group were significantly shorter than those of the control group(P<0.05).The levels of WBC,CRP and PCT in the two groups were lower than those before treatment(P<0.05),and those in the observation group were significantly lower than those in the control group(P<0.05).During the treatment period,one patient in the treatment group had transient dizziness and nause-a after the first oral administration of traditional Chinese medicine,and the blood pressure was normal,which relieved spontane-ously after rest.No obvious adverse reactions occurred in the control group.Conclusion:Sangma Erchong Decoction in the treat-ment of CAP can improve the curative effect,shorten the course of disease,reduce the level of inflammatory factors,and has no obvious adverse reactions.

Community acquired pneumoniaSyndrome of wind-heat invading lungSangma Erchong decoctionClinical efficacy

薛奇明、雍凤娇、刘菥、宋登丽、张晓慧

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四川省中西医结合医院呼吸内科,四川成都 610041

社区获得性肺炎 风热犯肺证 桑麻二虫汤 临床疗效

四川省中医药局科学技术研究专项

2020LC0192

2024

四川中医
四川省中医药学会,四川省中西医结合学会,四川省针灸学会,四川省中医药科学院

四川中医

CSTPCD
影响因子:0.522
ISSN:1000-3649
年,卷(期):2024.42(1)
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