Efficacy and safety evaluation of Dang gui si ni Tangof prevention of lower extremity deep vein thrombosis in ortho-paedic trauma patients during postoperative period
Objective:To analyze the efficacy and safety of Danggui Sini Tang in the prevention and treatment of lower limb deep vein thrombosis(DVT)in trauma orthopedic patients during the perioperative period.Methods:A total of 108trauma pa-tients admitted to our orthopedics department from January 2020to June 2023were selected.They were randomly divided into two groups(n=54in each group)using a random number table.The control group received lower limb pneumatic compression therapy combined with rivaroxaban treatment,while the observation group received lower limb pneumatic compression therapy combined with Danggui Sini Tang treatment.The degree of lower limb swelling,pain,coagulation function indicators,DVT incidence,length of hospital stay,and overall incidence of adverse reactions were compared between the two groups.Results:The rates of mild and moderate swelling in the observation group(37.04％,55.56％)were higher than those in the control group(11.11％,37.04％),while the rate of severe swelling in the observation group(7.41％)was lower than that in the control group(51.85％),with P＜0.05.The rates of mild and moderate pain in the observation group(29.63％,33.33％)were higher than those in the control group(0％,12.96％),while the rates of severe and extremely severe pain in the observation group(37.04％,0％)were lower than those in the control group(42.59％,44.44％),with P＜0.05.The levels of D-dimer(D-D)and fibrinogen(FIB)after treatment were lower in the observation group than in the control group,while the activated partial thromboplastin time(APTT)in the observation group was higher than that in the control group,with P＜0.05.The incidence of DVT in the observation group(1.85％)was lower than that in the control group(14.81％),with P＜0.05.The length of hospital stay in the observation group was shorter than that in the control group,with P＜0.05.The overall incidence of adverse reactions in the observation group(7.41％)was not significantly different from that in the control group(3.70％),with P＞0.05.Conclu-sion:Danggui Sini Tang can effectively reduce postoperative lower limb swelling and pain,improve coagulation function indica-tors,reduce the incidence of DVT,shorten the treatment time,and the medication is safe and effective without obvious adverse reactions in patients with trauma orthopedics.
Dang gui si ni Tangorthopedicslower limb deep vein thrombosissafety
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