穴位埋线结合降糖药对糖尿病患者胰高血糖素样肽-1水平的影响
Effect of acupoint catgut embedding combined with antidiabetic drugs on glucagon-like peptide-l level in diabetic patients
张璐 1范丹 1岳珊 1马界1
作者信息
- 1. 四川省中医药科学院中医药研究所,四川成都 610031
- 折叠
摘要
目的:探讨穴位埋线结合降糖药对糖尿病患者胰高血糖素样肽-1(GLP-1)水平的影响.方法:将74例糖尿病病患者随机分为降糖药加穴位埋线组、穴位埋线组和降糖药组3组,观察患者的胰高血糖素样肽-1(GLP-1)水平变化.结果:降糖药加穴位埋线组患者的胰高血糖素样肽-1(GLP-1)水平治疗前后对比有统计学意义(P＜0.05),且治疗后降糖药加穴位埋线组与穴位埋线组、降糖药组比较差异均有统计学意义(P＜0.05).通过观察对比三组糖尿病患者治疗前后GLP-1水平,评判治疗效果,降糖药加穴位埋线组有效率92.00％,穴位埋线组有效率66.67％,降糖药组有效率80.00％.降糖药加穴位埋线组有效率高于穴位埋线组、降糖药组,且有统计学意义(P＜0.05).结论:穴位埋线结合降糖药对糖尿病具有显著临床疗效.这可能是通过调节患者胰高血糖素样肽-1(GLP-1)的水平来实现的.
Abstract
Objective:To investigate the effect of acupoint catgut embedding combined with antidiabetic drugs on the level of glucagon-like peptide-1(GLP-1)in diabetic patients.Methods:74diabetic patients were randomly divided into three groups:antidiabetic drugs combined with acupoint catgut embedding group,acupoint catgut embedding group and antidiabetic drugs group,and the level of glucagon-like peptide-1(GLP-1)was observed.Results:The levels of glucagon-like peptide-1(GLP-1)in the antidiabetic drugs combined with acupoint catgut embedding group has a statistically significant difference before and after treatment(P＜0.05),and there were statistically significant differences between the antidiabetic drugs combined with acupoint catgut embedding group,acupoint catgut embedding group and antidiabetic drugs group after treatment(P＜0.05).By comparing the levels of GLP-1 in the three groups of diabetes patients before and after treatment,the treatment effect was evalua-ted.The effective rate of the antidiabetic drugs combined with acupoint catgut embedding group was 92.00％,the effective rate of the acupoint catgut embedding group was 66.67％,and the effective rate of the antidiabetic drugs group was 80.00％.The effec-tive rate of the antidiabetic drugs combined with acupoint catgut embedding group was higher than the acupoint catgut embedding group and the antidiabetic drugs group,with statistical significance(P＜0.05).Conclusion:Acupoint catgut embedding com-bined with antidiabetic drugs has significant clinical effect on diabetes.This may be achieved by regulating patients'levels of glu-cagon-like peptide-1(GLP-1).
关键词
穴位埋线/降糖药/糖尿病/胰高血糖素样肽-1Key words
acupoint catgut embedding/antidiabetic drugs/diabetes/glucagon-like peptide-1引用本文复制引用
基金项目
四川省科技厅基本科研项目(2020JDKY0031)
出版年
2024
国家科技期刊平台
NSTL
万方数据