Evaluation of quality of life and its correlation with risk factors in patients with chronic heart failure with different TCM syndromes
Objective:To investigate the differences in cardiac function indicators and quality of life in patients with chronic heart failure(CHF)with different TCM syndrome types,and the correlation between different TCM syndrome types and CHF risk factors.Methods:100patients with chronic heart failure aged 60~90who were admitted to our hospital from June 2018to June 2023were selected as the research objects,including 31cases of Qi deficiency and blood stasis syndrome and 23cases of Yang Qi deficiency and blood stasis syndrome 22cases of heart-yang deficiency and blood stasis syndrome,18cases of Qi and Yin deficien-cy and blood stasis syndrome,and 6cases of phlegm and blood stasis syndrome.Collect relevant information such as symptoms,tongue and pulse,heart function classification,heart failure stratification,heart function-related index detection data and health scale 36(SF-36scale)scores of patients with various syndrome types,and make statistics on the collected data To analyze and explore the quality of life of patients with different TCM syndrome types and its correlation with risk factors.Results:(1)Among the 5different types of TCM syndrome differentiation and treatment,the distribution ratio of each type of heart function level and each type of heart failure level was significant(P<0.05).The heart function scores of grades Ⅰ,Ⅲ and Ⅳ were 18.00%,51.00%,and 31.00%,among which the patients with grade Ⅱ had the highest proportion of Yang Qi deficiency and blood stasis syndrome(10,43.48%),and the patients with grade Ⅲ had Qi deficiency and blood stasis syndrome.The proportion was the highest(17,54.84%),and the highest proportion was heart yang deficiency and blood stasis in patients with grade Ⅳ(9,40.91%);in the stratification of heart failure,patients with heart failure with reduced ejection fraction(HFrEF)were divided into Qi and Yin Deficiency and blood stasis syndrome accounted for the highest proportion(6,33.33%),patients with heart fail-ure with borderline ejection fraction(HFmrEF)had the highest proportion of qi deficiency and blood stasis syndrome(16,51.61%),heart failure with preserved ejection fraction(HFpEF)The heart-yang deficiency and blood stasis syndrome accoun-ted for the highest proportion(10,45.45%).(2)There was no statistical significance in the levels of LVDD and LVEF among the five syndrome types(P>0.05),but there was a statistically significant difference in the levels of N-terminal-proB-type na-triuretic peptide(NT-proBNP)(P<0.05).(3)The PF score of Qi deficiency and blood stasis syndrome in the SF-36scale score of each syndrome type was significantly higher than that of other syndrome types(P<0.05);the GH score of Qi deficiency and blood stasis syndrome was significantly lower than that of other syndrome types(P<0.05);the VT score of Qi deficiency and blood stasis syndrome was significantly higher than that of Qi and Yin deficiency and blood stasis syndrome(P<0.05).(4)In"blood stasis syndrome",coronary heart disease(OR=2.236)and arrhythmia(OR=1.582)were the main risk factors(P<0.05or P<0.01).Among them,coronary heart disease has a greater impact,and there is a significant correlation between the TCM syndrome types of CHF patients and coronary heart disease and heart valve disease(P<0.05or P<O.01).Conclusion:In CF,qi deficiency and blood stasis syndrome is a relatively stable period,mainly grade Ⅲ,and NT-proBNP content is low.Dur-ing the transition from qi-deficiency and blood-stasis syndrome to other syndrome types,the proportion of cardiac function catego-ry Ⅳ gradually increased,while the content of NT-proBNP showed an upward trend;cardiac function classification and TCM syn-drome types are closely related to the quality of life of heart failure patients Blood stasis is more common in heart failure with coro-nary heart disease and arrhythmia;qi deficiency is more common in hypertension with coronary heart disease and valvular disease;yang deficiency is more common in hypertension with DCM.
chronic heart failurerisk factorsquality of lifeTCM syndrome types