Effect of YunXuNeiLe BianZheng for refractory fever after large dose methylprednisolone for cervical spinal shock
Objective:To investigate the effect of YunXuNeiLe BianZhengfor refractory fever after large dose methylpred-nisolone for cervical spinal shock.Method:Between October 2003and January 2022,63patients with refractory fever after large dose methylprednisolone for cervical spinal shock were treated in 910th hospital of Chinese PLA,and all patients belonged to YunXuNeiLeZheng.30patients in control group were treated with conventional therapies,and 33patients in observation group were treated with QingGuSan.Preoperative and afteroperative score of traditional medical syndrome(STMS),effective rate,time to onset and inflammation indicators were recorded.Result:In observational group,afteroperative STMS was superior to pre-operative(P<0.01),but in control group there was no significant difference between preoperative and afteroperative STMS(P>0.05).Preoperative STMS in observation group was similar to control group(P>0.05),but afteroperative STMS was lower than control group(P<0.01).Effective rate in observation group(87.88%)was superior to control group(10.00%)(P<0.01),and time to onset(4.27±1.05)days was lower than control group(8.67±2.08)days(P<0.01).Erythrocyte sedimentation rate(ESR)and C-reactive protein(CRP)in observation group was lower than control group(P<0.01),but white blood cell count(WBC)was similar to control group(P>0.05).Conclusion:For refractory fever after large dose methylprednisolone for cervical spinal shock,on the basis of conventional therapies,QingGuSan can increase cure rate,and reduce treatment time,and it was worthy of promotion because of its significant effect.