Study on Diabetic Nephropathy Evidence Elements and Medication Pattern Based on the Analysis of Modern Chi-nese Medical Case Literature
Objective:To analyze the incidence population,core symptoms,syndrome types,syndrome elements and medi-cation rules of diabetic nephropathy(DN)by using data mining technology.Methods:Chinese medical records were searched in the database of CNKI,and 340valid literatures and 394prescriptions were included to construct the database.The co-occurrence and correlation data were analyzed by Python,Gephi,SPSS and other software.Results:The incidence of DN was mainly 45~75years old men.The core symptoms of the patient were fatigue,dry mouth,lower limb edema,etc.The early stage of DN was mainly in liver and kidney,and the later stage was mainly in spleen and kidney.Qi deficiency,blood deficiency,Yang deficien-cy,dampness and Yin deficiency are the most common diseases.The most commonly used pairs are Astragalus-Poria,Astraga-lus-Yam,and Astragalus-Sanjus.Conclusion:The basic pathogenesis of diabetic nephropathy is based on zang fu deficiency syndrome of liver,spleen and kidney,mixed with cold,heat,dampness and blood stasis.The treatment mainly focuses on invig-orating qi and nourishing Yin and tonifying liver and kidney.
Diabetic NephropathyTraditional Chinese MedicineData miningCo-occurrence analysisMedication rulesLiterature research of medical cases