从"二本三枢"论治慢性阻塞性肺疾病合并阻塞性睡眠呼吸暂停低通气综合征
Treatment of Chronic Obstructive Pulmonary Disease combined with Obstructive Sleep Apnea-hypopnea Syndrome Based on the Theory of"Two Bases and Three Pivots"
刘美苹 1曹龙 2张心月 3何荣 4朱雪 4邵雨萌1
作者信息
- 1. 山东中医药大学,山东济南 250355
- 2. 日照市中医医院,山东 日照 276800
- 3. 山东中医药大学,山东济南 250355;山东中医药大学附属医院,山东济南 250014
- 4. 山东中医药大学附属医院,山东济南 250014
- 折叠
摘要
从"二本三枢"理论出发,对慢性阻塞性肺疾病(chronic obstructive pulmonary disease,COPD)合并阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apnea-hypopnea syndrome,OSAHS),即重叠综合征(overlap syndrome,OVS)的病机进行探讨.提出二本不足、本源亏虚是OVS发病的关键病机,枢机不利、气血津液代谢失调是OVS发病的核心病理环节.主张根据COPD缓解期和急性期合并OSAHS的不同特点进行分期论治.缓解期以脾肾本源不足为核心,以补先天,养后天为治疗原则;急性期以痰瘀阻滞气机,肺失宣降为核心,以和枢机,解郁结为治疗原则.
Abstract
The study discussed the pathogenesis of the chronic obstructive pulmonary disease(COPD)combined with ob-structive sleep apnea-hypopnea syndrome(OSAHS)based on the theory of"two bases and three pivots".COPD combined with OSAHS is also named overlap syndrome(OVS).The deficiency of"two bases"is the core pathogenesis of OVS.The inharmony of"three pivots"and the imbalance of metabolism in qi,blood,and body fluid is the core pathological link of OVS.We advocate staged treatment according to the different characteristics of COPD in remission and acute stage combined with OSAHS.In the re-mission stage,the core pathogenesis is the deficiency of the spleen and kidney,and the principle of treatment is to nourish the in-nate and the acquired;in the acute stage,the core pathogenesis is phlegm and blood stasis obstructing ascending and descending of qi,and the principle of treatment is to harmonize principal axis and regulate stagnation and inversion of qi.
关键词
慢性阻塞性肺疾病合并阻塞性睡眠呼吸暂停低通气综合征/二本/三枢Key words
chronic obstructive pulmonary disease combined with obstructive sleep apnea-hypopnea syndrome/two bases/three pivots引用本文复制引用
基金项目
国家自然科学基金青年科学基金(81503547)
山东省中医药科技发展计划(2019-0125)
出版年
2024
国家科技期刊平台
NSTL
万方数据