摘要
目的:探讨经验灌肠方联合微波对湿热瘀结型盆腔炎性疾病后遗症(SPID)的治疗效果.方法:选择120例湿热瘀结型SPID患者为研究对象,按随机数字表法分为对照组60例康妇消炎栓联合微波治疗,观察组60例经验灌肠方联合微波治疗,共治疗2疗程.记录治疗前后彩超检查结果,测定CD4+、CD8+、CD4+/CD8+、白细胞数、中性粒细胞比例,视觉模拟评分法(VAS)评估下腹部疼痛、腰骶部酸胀疼痛、经期腹痛程度,并观察两组患者生活质量及临床疗效.结果:治疗后观察组盆腔积液程度好于对照组,盆腔炎性包块小于对照组,血液流变学改善优于对照组(P＜0.05).治疗后观察组CD4+、CD4+/CD8+高于对照组,CD8+、白细胞数、中性粒细胞比例小于对照组(P＜0.05).治疗后观察组下腹部疼痛、腰骶部酸胀疼痛、经期腹痛程度低于对照组,生活质量改善(P＜0.05).对照组总有效率86.67％(52/60)低于观察组总有效率96.67％(58/60)(P＜0.05).结论:经验灌肠方联合微波治疗SPID疗效较好,可明显改善临床症状、体征及血液流变学,并提高患者生活质量,调节细胞免疫功能,安全性较高.
Abstract
Objective:To explore the efficacy of Jingyan Guanchang Fang combined with microwave therapy in the treatment of sequelae of pelvic inflammatory disease(SPID)of dampness heat stasis type.Method:120patients with dampness heat stasis type SPID were selected as the research subjects and randomly divided into a control group of 60cases treated with Kangfu Xiaoyan Suppository combined with microwave therapy,and an observation group of 60cases treated with experiential enema formula com-bined with microwave therapy,for a total of 2courses of treatment.Record the results of color Doppler ultrasound before and after treatment,measure CD4+,CD8+,CD4+/CD8+,white blood cell count,and neutrophil ratio,evaluate the degree of lower ab-dominal pain,lumbosacral soreness and pain,and menstrual abdominal pain using Visual Analog Scale(VAS),and observe the quality of life and clinical efficacy of the two groups of patients.Result:After treatment,the degree of pelvic effusion in the obser-vation group was better than that of the control group,the pelvic inflammatory mass was less than that of the control group,and the improvement of blood rheology was better than that of the control group(P＜0.05).After treatment,the CD4+and CD4+/CD8+levels in the observation group were higher than those in the control group,while the CD8+,white blood cell count,and neutrophil ratio were lower than those in the control group(P＜0.05).After treatment,the degree of lower abdominal pain,lum-bosacral soreness,and menstrual abdominal pain in the observation group was lower than that in the control group,improved qual-ity of life(P＜0.05).The total effective rate of the control group was 86.67％(52/60),which was lower than the observation group's total effective rate of 96.67％(58/60)(P＜0.05).Conclusion:Jingyan Guanchang Fang combined with microwave ther-apy is effective in the treatment of SPID,which can significantly improve the clinical symptoms,signs and Hemorheology,im-prove the quality of life of patients,regulate cellular immune function,and have high safety.
基金项目
重庆市科卫联合中医药技术创新与应用发展项目(2021ZY4111)
国家科技期刊平台
NSTL
万方数据