The Effect of Jianpi Buzhong Huazhuo Tang combined with Western medicine on immune function and short-term prognosis of patients undergoing radical gastrectomy for gastric cancer
Objective To explore the influence of Jianpi Buzhong Huazhuo decoction on immune function and short-term prognosis in patients undergoing radical resection of gastric cancer.Methods A total of 35postoperative patients with gastric cancer admitted to the research hospital from January 2020to January 2023were randomly divided into a control group(n=17,conven-tional treatment combined with Western medicine treatment)and a study group(n=18,control group combined with Jianpi Buzhong Huazhuo Tang treatment)using a random number table method.The TCM symptom scores,therapeutic effects,gastroin-testinal function,immune function,recent prognosis,and adverse reactions of the two groups of patients were compared..Results(1)Compared with before treatment,the TCM symptoms scores in the two groups were decreased after treatment(P＜0.05),and the scores were lower in study group(P＜0.05).(2)The total effective rate in study group was higher compared with that in con-trol group(P＜0.05).(3)The levels of gastrin and motilin in both groups were increased after treatment compared with those be-fore treatment,and the levels in study group were higher(P＜0.05).Compared with before treatment,the somatostatin level was declined after treatment in both groups,and the level in study group was lower compared to control group(P＜0.05).(4)After treatment,the levels of CD4+and natural killer cell(NK)in the two groups were enhanced compared with those before treatment,and the study group had higher CD4+and NK(P＜0.05).(5)There were no statistical differences in short-term prognosis and adverse reactions between the two groups(P＞0.05).Conclusion Jianpi Buzhong Huazhuo decoction can improve the TCM symp-toms and short-term prognosis of patients after radical resection of gastric cancer,and it is conducive to improving the therapeutic efficacy,gastrointestinal function and immune function,and it has high safety.
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