目的:探究火龙罐在椎动脉型颈椎病(CSA)护理的临床疗效及潜在的作用机制.方法:选择苏州市中西医结合医院2022年6月～2023年6月收治的CSA患者60例进行临床研究,按照随机数字表法分为对照组(电针+常规护理)和治疗组(在对照组的基础上联合火龙罐治疗),两组均治疗4周.观察两组患者治疗前后眩晕症状与功能评分(evaluation scale for cervical vertigo,ESCV);比较两组患者血流动力学指标的变化,包括椎动脉[左侧椎动脉(LVA)、右侧椎动脉(RVA)、基底动脉(BA)]平均血流速度(Mean Velocity,Vm)、血管搏动指数(Pulsation In-dex,PI)、脑血管阻力指数(Resistance Index,RI)的变化;对比两组患者血清中血清血栓素A2(Thromboxane A2,TXA2)、内皮素(Endothelin,ET)水平的变化;比较两组患者治疗后的临床疗效并进行安全性评价.结果:治疗后与治疗前相比,两组患者ESCV评分升高(P＜0.05);两组患者LVA、RVA、BA的Vm值均升高(P＜0.05),RI值、PI值均下降(P＜0.05);两组患者血清中TXA2、ET水平降低(P＜0.05).治疗后与对照组相比,治疗组患者的ES-CV评分升高更显著(P＜0.05);治疗组患者LVA、RVA、BA的Vm值升高更明显(P＜0.05),RI、PI值下降也更明显(P＜0.05);治疗组患者血清中TXA2、ET水平下降更显著(P＜0.05).治疗组的总有效率明显优于对照组(P＜0.05),且无不良事件发生.结论:在常规护理基础上联合火龙罐治疗,能够更有效的改善CSA患者的临床症状,其作用机制可能与能够降低血清中TAX2、ET水平有关.
Study on clinical efficacy and mechanism of Huolong pot in nursing of vertebral artery type cervical spondylosis
Objective:To explore the clinical effect and potential mechanism of Huolong pot nursing in vertebral artery type cervical spondylosis(CSA).Method:Sixty patients with CSA admitted to Suzhou Hospital of Integrated Chinese and Western Medicine from June 2022to June 2023were selected for clinical study.According to random number table method,they were divid-ed into control group(electroacupuncture+routine nursing)and treatment group(combined with Huolong pot treatment on the basis of control group).Both groups were treated for 4weeks.The evaluation scale for cervical vertigo(ESCV)was observed be-fore and after treatment.The changes of hemodynamic indexes of the two groups were compared,including the Mean Velocity(Vm)and Pulsation Index of the vertebral artery(left vertebral artery(LVA),right vertebral artery(RVA)and basilar artery(BA))of the two groups.PI),cerebral vascular Resistance Index(RI)changes;The changes of Thromboxane A2(TXA2)and Endothelin(ET)in serum of the two groups were compared.The clinical efficacy and safety of the two groups were compared after treatment.Result:After treatment,compared with before treatment,ESCV score was increased in two groups(P＜0.05).Vm values of LVA,RVA and BA were increased(P＜0.05),while RI and PI values were decreased(P＜0.05)in both groups.Serum levels of TXA2and ET in 2groups were decreased(P＜0.05).After treatment,the ESCV score of the treatment group was significantly higher than that of the control group(P＜0.05).In the treatment group,Vm values of LVA,RVA and BA increased more significantly(P＜0.05),and RI and PI values decreased more significantly(P＜0.05).The serum levels of TXA2and ET in the treatment group were significantly decreased(P＜0.05).The total effective rate of the treatment group was significantly better than that of the control group(P＜0.05),and no adverse events occurred.Conclusion:On the basis of routine nursing,combined with Huolong pot therapy can improve the clinical symptoms of CSA patients more effectively,and the mechanism of action may be related to reducing the levels of TAX2and ET in serum.
Vertebral artery type cervical spondylosisHuolong potTraditional Chinese medicine nursingClinical re-search
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