首页|半夏白术天麻汤合通窍活血汤联合治疗痰瘀互结型高血压颈动脉斑块疗效及对中医证候积分和血脂代谢的影响

半夏白术天麻汤合通窍活血汤联合治疗痰瘀互结型高血压颈动脉斑块疗效及对中医证候积分和血脂代谢的影响

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目的:观察半夏白术天麻汤合通窍活血汤联合治疗痰瘀互结型高血压(HTN)颈动脉斑块疗效及对中医证候积分和血脂代谢的影响。方法:选取我院 2021 年 1 月~2022 年 6 月收治的HTN伴颈动脉斑块患者 62 例。按照随机数字表法将患者分为治疗组(n=31)与对照组(n=31),两组均予以基础治疗,对照组以西药服用治疗,治疗组以西药+半夏白术天麻汤合通窍活血汤治疗,比较治疗后临床疗效,治疗前后中医症候积分、血压监测、血脂水平、超声检查[颈动脉内膜-中层厚度(IMT)、Grouse积分]、实验室指标[同型半胱氨酸(Hcy)、C反应蛋白(CRP)]。结果:治疗 4 个疗程后,治疗组临床疗效为 28/31(90。32%)较对照组 22/31(70。97%)更高(P<0。05);两组中医证候积分、收缩压(SBP)、舒张压(DBP)、低密度脂蛋白(LDL-C)、总胆固醇(TC)、甘油三酯(TG)、IMT、Crouse积分、血清 Hcy、CRP 水平均降低(P<0。05),且治疗组降幅高于对照组(P<0。05);两组高密度脂蛋白(HDL-C)均升高(P<0。05),且治疗组升幅高于对照组(P<0。05)。结论:半夏白术天麻汤合通窍活血汤联合治疗痰瘀互结型HTN伴颈动脉斑块可通过调节血脂代谢及血压水平,有效促进斑块消除,进而改善患者临床症状。
Efficacy of Banxia Baizhu Tianma decoction combined with Tongqiao Huoxue decoction on intermingled phlegm and blood stasis type of hypertension with carotid plaques and its influence on TCM syndromes scores and blood lipid metabolism
To explore the efficacy of Banxia Baizhu Tianma decoction combined with Tongqiao Huoxue decoction in the treat-ment of intermingled phlegm and blood stasis type of hypertension(HTN)with carotid plaques and the influence on TCM syn-dromes scores and blood lipid metabolism.Methods:62patients with HTN and carotid plaques in our hospital from January 2021to June 2022were selected.According to the random number table method,the patients were divided into treatment group(n=31)and control group(n=31).Both groups were given basic treatment,and the control group was treated with western medicine while the treatment group was given western medicine+Banxia Baizhu Tianma decoction with Tongqiao Huoxue decoction.The clinical efficacy after treatment and TCM symptoms scores,blood pressure monitoring,blood lipids levels,ultrasound examination[carotid intima-media thickness(IMT),Grouse score]and laboratory indicators[homocysteine(Hcy),C-reactive protein(CRP)]before and after treatment were compared.Results:After 4courses of treatment,the clinical efficacy in treatment group was 28/30(90.32%),which was higher than 22/31(70.97%)in control group(P<0.05).The TCM syndromes scores,sys-tolic blood pressure(SBP),diastolic blood pressure(DBP),low-density lipoprotein cholesterol(LDL-C),total cholesterol(TC),triglyceride(TG),IMT,Crouse score,serum Hcy and CRP were decreased in the two groups(P<0.05),and the de-creases were higher in treatment group(P<0.05).The high-density lipoprotein cholesterol(HDL-C)in both groups was in-creased(P<0.05),and the increase was higher in treatment group than that in control group(P<0.05).Conclusion:Banxia Baizhu Tianma decoction combined with Tongqiao Huoxue decoction can effectively promote the plaque elimination by regulating blood lipid metabolism and blood pressure in treating intermingled phlegm and blood stasis type of HTN with carotid plaques,thereby improving the clinical symptoms of patients.

Banxia Baizhu Tianma decoctionTongqiao Huoxue decoctionIntermingled phlegm and blood stasis typeHy-pertensionCarotid plaquesTCM Syndrome PointsLipid metabolism

王静、唐晓敏、程超超、姚舒雅

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合肥市第一人民医院中医科,安徽 合肥 230061

半夏白术天麻汤 通窍活血汤 痰瘀互结型 高血压 颈动脉斑块 中医证候积分 血脂代谢

2024

四川中医
四川省中医药学会,四川省中西医结合学会,四川省针灸学会,四川省中医药科学院

四川中医

CSTPCD
影响因子:0.522
ISSN:1000-3649
年,卷(期):2024.42(7)