Effect of TiaoshenYizhi decoction combined with biofeedback on serum ACTH and CORT levels in school-age chil-dren with attention deficit hyperactivity disorder
Objective:To explore the effect of Tiaoshen Yizhi decoction combined with biofeedback on attention concentration degree and levels of serum adrenocorticotrophic hormone(ACTH)and cortisol(CORT)in school-age children with attention deficit hyperactivity disorder(ADHD)(spleen deficiency and liver hyperactivity syndrome).Methods:140school-age children with ADHD(spleen deficiency and liver hyperactivity syndrome)admitted to the hospital from January 2020to December 2021were selected as observation subjects,and were divided into observation group and control group by the simple randomization method,with 70cases in each group.The control group was treated with biofeedback,and the observation group was given Tiaosh-en Yizhi decoction.The changes in TCM symptoms scores,attention concentration[Swanson,Nolan,and Pelham,Version IV(SNAP-IV),serological indicators(ACTH,CORT)and cognitive status[Chinese version of Wechsler Intelligence Scale for Children(C-WISC)]were compared between the two groups before treatment and after 3months of treatment.Results:After 3months of treatment,the TCM syndromes scores and SNAP-IV scores in the two groups were significantly decreased,and the scores in observation group were lower than those in control group(P<0.05).Serum ACTH levels and C-WISC scores were sig-nificantly increased in both groups,and the levels and scores in observation group were higher than those in control group(P<0.05).The effective rate of treatment in observation group was higher than that in control group(P<0.05).Conclusion:Tiaosh-en Yizhi decoction combined with biofeedback has a significant efficacy on school-age children with ADHD,and it can effectively improve the attention control and is beneficial to the prognosis of children.
Tiaoshen Yizhi decoctionBiofeedbackAttention deficit hyperactivity disorderSpleen deficiency and liver hy-peractivitySNAP-IV