Efficacy of Sixian Granules in the Treatment of Thrombocytopenia After Chemotherapy
PURPOSE:Most of the anti-tumor chemotherapy drugs can cause hematopoietic dysfunction of bone marrow in patients,which often leads to treatment that cannot be performed on time and according to the amount,which affects the effect of chemotherapy.Thrombocytopenia is one of the manifestations of inhibition of bone marrow function.Although subcutaneous injec-tion of"interleukin-11"and"TPO"is effective in improving platelets,it is clinically limited due to high price.There are few re-ports of effective treatment of thrombocytopenia after chemotherapy with oral,relatively inexpensive drugs.This study explored treatment effect of the author's self-made Chinese medicine"Sixian Granule"on thrombocytopenia after chemotherapy.METH-ODS:A total of 65patients with thrombocytopenia after chemotherapy were observed from February 2015to December 2016.Among them,33patients who whtook 1dose of"Sixian Granules"3times a day for 2weeks in addition to conventional symptomatic treat-ment were in the treatment group.In the control group,32patients were treated with conventional symptomatic treatment for 2weeks.RESULTS:The significant efficiency of the treatment group was 21.2%,the effective rate was 51.5%,and the total ef-fective rate was 73.7%.The significant efficiency of the control group was 12.5%,the effective rate was 37.5%,and the total ef-fective rate was 25.0%.There was significant difference between the two groups(P＜0.01).CONCLUSION:"Sixian Granule"can effectively increase the decreased platelet level after chemotherapy.
tumorchemotherapythrombocytopeniatraditional Chinese medicine
万方数据
维普
