Effects of auricular acupoint compression bean combined with liver-soothing Chinese medicine on IOP,visual field defect and ocular blood flow in patients with primary open Angle glaucoma of liver-depression type
Objective To observe the effects of auricular acupoint pressure on intraocular pressure,visual field defect and oc-ular blood flow in patients with primary open Angle glaucoma(POAG)with liver depression.Methods A total of 110patients with hepatic depression type POAG admitted to our hospital from February 2020to May 2023were divided into two groups by simple random method.In the basic group,55cases(110eyes)were given basic Western medicine treatment,and in the traditional Chi-nese medicine treatment group,55cases(110eyes)were given auricular point compression bean combined with liver soothing Chi-nese medicine treatment on the basis of basic group.The diurnal intraocular pressure,mean visual field defect,trans-mesh plate pressure difference(TCLPD),visual field index(VFI),optic disc optical coherence tomography(OCT)indexes[disk area,vertical C/D ratio,optic cup volume,retinal fiber layer thickness(RNFLT)],ocular blood flow and TCM syndrome score were compared between the two groups.Results There were no significant differences between day and night iOP,average visual field defect,optic disc OCT,TCLPD and VFI before treatment(P＞0.05).After treatment,the mean visual field defect,TCLPD and IOP at 7,14and 21 points were lower in both groups than before treatment,and the mean visual field defect and TCLPD were low-er in the TCM treatment group(P＜0.05).After treatment,VFI and RNFLT were increased in the two groups,and higher in the Chinese medicine treatment group(P＜0.05).There were no differences in the disk rim area,vertical C/D ratio and visual cup volume between the two groups before and after treatment(P＞0.05).There was no difference in eye blood flow before treatment(P＞0.05).After treatment,the end-diastolic blood flow velocity(EDV)and peak systolic blood flow velocity(PSA)of the central retinal artery and posterior ciliary artery were higher than those before treatment in the two groups,and those in the tradi-tional Chinese medicine treatment group were higher(P＜0.05).The resistance index(RI)of central retinal artery and posterior ciliary artery was lower in two groups after treatment,and lower in TCM group(P＜0.05).There was no difference in TCM syn-drome score before treatment(P＞0.05).After treatment,the scores of dim vision,slightly dilated eyes,larger pupils,emotional discomfort,chest pain,dry mouth,bitter mouth,tinnitus and constipation were lower in the two groups,and lower in the Chinese medicine treatment group(P＜0.05).Conclusion The treatment of POAG of liver depression can relieve symptoms,reduce day and night intraocular pressure,improve eye blood circulation and enhance visual field.
Auricular point pressure beanHerbal therapy for soothing liverLiver depression typePrimary open-angle glaucomaEye blood flow
万方数据
维普
