Effects of of internal and external administration of Huayu Quyou Decoction on TCM syndromes,serum immuno-globulins and recurrence in patients with flat wart
Objective To explore the effects of internal and external administration of Huayu Quyou Decoction on TCM syn-dromes,serum immunoglobulins and recurrence in patients with flat wart.Methods A total of 132patients with flat wart were en-rolled as the research objects between August 2021 and August 2023.According to random number table method,they were divid-ed into observation group and control group,66cases in each group.The control group was treated with routine drugs,while obser-vation group was additionally treated with Huayu Quyou Decoction for internal and external administration.The clinical curative effect,scores of TCM syndromes(color of skin rash,itching,general fever and dry mouth,dry stool and yellow urine),serum immunoglobulins[immunoglobulin G(IgG),immunoglobulin A(IgA),immunoglobulin M(IgM)],immune cytokines[inter-leukin-2(IL-2),interleukin10(IL-10),interferon γ(IFN-γ)]and recurrence rate were compared between the two groups.Results The total response rate of observation group was higher than that of control group(P＜0.05).After treatment,scores of TCM syndromes(color of skin rash,itching,general fever and dry mouth,dry stool and yellow urine)in observation group were lower than those in control group(t=6.114;t=5.552;t=6.705;t=5.435,P＜0.05),levels of serum IgG,IgA and IgM were higher than in control group(t=4.056;t=3.630;t=5.918,P＜0.05),levels of IFN-γ and IL-2were higher than those in control group,while IL-10level was lower than in control group(t=9.462;t=5.429;t=8.314,P＜0.05).After 6months of follow-up,recurrence rate of observation group was lower than that of control group(4.55％vs 16.67％,x2=5.114,P＜0.05).Conclusion Curative effect of internal and external administration of Huayu Quyou Decoction is significant in patients with flat wart,which can effectively increase levels of immunoglobulins,improve immune cytokines and reduce recurrence rate.
万方数据
维普
