Relationship between TCM syndrome type distribution and serum Th1/Th2,lung function and CAT score in pa-tients with AECOPD
Objective:To explore the relationship between TCM syndrome type distribution and serum helper T cell 1/Help-er T cell 2(Th1/Th2),lung function and chronic obstructive pulmonary disease evaluation test(CAT)score in patients with a-cute exacerbation of chronic obstructive pulmonary disease(AECOPD).Methods:A total of 114 patients with AECOPD admitted to our hospital between March 2021 and March 2023 were included in the study.TCM syndrome differentiation was performed on the patients according to clinical symptoms,and clinical data of patients with different syndrome differentiation types were collect-ed for retrospective analysis.The serum Th1/Th2,lung function and CAT scores of patients with different syndrome differentiation types were compared.Results:The clinical distribution of AECOPD patients was mainly divided into 5 syndrome types,namely,phlegm turbidity obstructing lung syndrome in 18 cases(15.79%),phlegm heat stagnation lung syndrome in 22 cases(19.30%),phlegm obstruction syndrome in 20 cases(17.54%),lung-kidney qi deficiency syndrome in 26 cases(22.81%),and Yang deficiency water syndrome in 28 cases(24.56%).The comparison of serum Th1/Th2 in the five groups of TCM syndrome patients showed that phlegm turbidity obstructing lung group>Phlegm heat stagnation lung group>Tanmeng Shenqi group>Lung-kidney qi deficiency group>Yang-deficiency Shuipan group(P<0.05).CAT scores of the five groups of TCM syndrome patients showed that phlegm turbidity obstructing lung group<Phlegm heat stagnation lung group<Phlegm Mengshenqi group<lung and kidney qi deficiency group<Yang deficiency Shuifang group(P<0.05);The comparison of FEV1,FEV1%and FEV1/FVC among the five groups of TCM syndrome patients showed that phlegm turbidity obstructing lung group>Phlegm heat stagnation lung group>Phlegm Mengshenqi group>Lung-kidney qi deficiency group>Yang-deficiency Shuipan group(P<0.05).Conclusion:Develops gradually with AECOPD patients,the symptoms and the lung spleen-deficiency progress to the lung spleen kidney deficiency,lung function and immune function decline accordingly.
Pulmonary functionChronic obstructive pulmonary disease assessment testChronic obstructive pulmonary diseases acute exacerbation periodHelper T cell 1/Helper T cell 2
万方数据
维普
