Distribution characteristics of TCM syndromes and differential value of MSCT perfusionimaging parameters in pa-tients with thyroid nodules
Objective To explore the distribution characteristics of TCM syndromes and the differential value of multi-slice spiral computed tomography(MSCT)perfusion imaging parameters in patients with thyroid nodule(TN).Methods A total of 130 patients with TN admitted to the hospital were enrolled between January 2021 and December 2022.All underwent CT plain scan and MSCT perfusion scan.TCM syndromes were classified according to the classification criteria.The composition ratios of TCM syndromes in TN patients were analyzed.The distribution characteristics and MSCT perfusion parameters[blood flow(BF),blood volume(BV),permeability surface(PS),mean transit time(MTT)]in TN patients with different TCM syndromes were compared.Results Among the 130 patients with TN,there were 35 cases with phlegm-blood stasis syndrome(26.92%),42 ca-ses with qi-stagnation phlegm obstruction syndrome(32.31%),33 cases with liver fire flourishing syndrome(25.39%)and 20 cases with heart-liver yin deficiency syndrome(15.38%).The age was the oldest in patients with phlegm-blood stasis syn-drome.BMI was the highest in patients with qi-stagnation phlegm obstruction syndrome,and most were accompanied with multi-ple nodules,with unclear boundaries.In patients with liver fire flourishing syndrome,there was punctal calcification in nodular le-sion tissues(P<0.05).PS was the lowest in patients with qi-stagnation phlegm obstruction syndrome,MTT was the longest in patients with heart-liver yin deficiency syndrome,and BF was the highest in patients with liver fire flourishing syndrome(P<0.05).Conclusion There are significant differences in age,BMI,number of nodules,nodule boundary and calcification among TN patients with different TCM syndromes.MSCT perfusion imaging parameters can be applied as objective indexes in the differ-ential diagnosis of TCM syndromes.