Observation on the therapeutic effect of the nourishing kidney,nourishing yang,and strengthening bone formula on patients with perimenopausal osteoporosis(kidney yin yang deficiency type)
Observation on the therapeutic effect of the nourishing kidney,nourishing yang,and strengthening bone formula on patients with perimenopausal osteoporosis(kidney yin yang deficiency type)
Objective:To explore the clinical effect of the Zishen Fuyang Jiangu formula in the treatment of perimenopausal osteoporosis(kidney yin yang deficiency type)patients.Method:92 patients with perimenopausal osteoporosis admitted to our hospital from June 2020 to June 2022 were randomly divided into an observation group(n=46)and a control group(n=46).The control group was treated with conventional Western medicine calcium carbonate D3 tablets,while the observation group was trea-ted with nourishing kidney,nourishing yang,and strengthening bone formula on the basis of it.After continuous treatment for 3 months,compare the efficacy of the two groups;Compare the TCM syndrome scores,bone density,and changes in bone metabo-lism between two groups;Compare the safety of medication between two groups.Result:After continuous treatment for 3 months,the total effective rate of the observation group was 97.83％,which was higher than the control group's 86.96％(P<0.05);Af-ter treatment,the TCM syndrome score,C-terminal peptide of type Ⅰ collagen,and anti tartaric acid phosphatase 5b levels in both groups decreased compared to before treatment,and the observation group was lower than the control group(P<0.05).The bone density of the L1-L4 lumbar spine,left femoral neck,and bone specific alkaline phosphatase levels in both groups increased compared to before treatment,and the observation group was higher than the control group(P<0.05);There was no statistically significant difference in the incidence of adverse drug reactions between the two groups(P>0.05).Conclusion:The Zishen Fuy-ang Jiangu Formula can effectively improve the actual treatment effect of perimenopausal osteoporosis(Kidney Yin Yang Deficien-cy Type),alleviate typical symptoms of patients,improve bone metabolism levels,increase bone density,and does not increase medication risk,with high safety.
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