首页|麻黄附子细辛汤合固本通窍汤对过敏性鼻炎患者免疫功能的影响

麻黄附子细辛汤合固本通窍汤对过敏性鼻炎患者免疫功能的影响

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目的:探究麻黄附子细辛汤合固本通窍汤对过敏性鼻炎患者免疫功能的影响.方法:选取 2020 年 9 月~2022 年 9 月与我院接收的过敏性鼻炎患者 102 例,按照随机数字法分为对照组、观察组各 51 例.所有患者均使用氯雷他定进行治疗,对照组患者使用固本通窍汤进行治疗,观察组患者使用麻黄附子细辛汤联合固本通窍汤对患者进行治疗.检测白细胞介素-4(IL-4)、白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)、免疫球蛋白E(IgE)、T辅助细胞(Th1/Th2)、最大呼气流量(PEF)和PEF变异率;观察对比两组患者中医证候评分、治疗有效率.结果:与对照组相比,观察组患者IgE降低、Th1/Th2 较高(P<0.05);与对照组相比,观察组患者主症评分及中医证候降低(P<0.05);与对照组相比,观察组患者血清IL-4、IL-6、TNF-α水平降低(P<0.05);与对照组相比,观察组PEF水平升高,PEF变异率降低(P<0.05);与对照组相比,观察组治疗总有效率上升(P<0.05).结论:使用麻黄附子细辛汤合固本通窍汤对过敏性鼻炎患者进行治疗,能够改善患者血清因子水平,提高患者的免疫功能,效果显著.
Effect of Ephedra fuzi Asarum Decoction and Guben Tongqiao Decoction on immune function of patients with aller-gic rhinitis
Objective:To explore the effect of Ephedrine Fuzi Asarum Decoction and Guben Tongqiaodang on immune func-tion in patients with allergic rhinitis.Methods:102 patients with allergic rhinitis admitted to our hospital from September 2020 to September 2022 were randomly divided into a control group and an observation group,with 51 cases in each group.All patients were treated with loratadine,the control group was treated with Guben Tongqiao Tang,and the observation group was treated with Mahuang Fuzi Xixin Tang combined with Guben Tongqiao Tang.Detection of interleukin-4(IL-4),interleukin-6(IL-6),and tumor necrosis factor-α TNF-α)、Immunoglobulin E(IgE),T helper cells(Th1/Th2),maximum expiratory flow(PEF),and PEF variability;Observe and compare the traditional Chinese medicine syndrome scores and treatment effectiveness between two groups of patients.Results:Compared with the control group,the observation group had a decrease in IgE and a higher Th1/Th2(P<0.05);Compared with the control group,the main symptom score and traditional Chinese medicine syndrome of the observa-tion group patients decreased(P<0.05);Compared with the control group,the serum IL-4,IL-6,TNF-α in the observation group patients α Horizontal decrease(P<0.05);Compared with the control group,the observation group showed an increase in PEF levels and a decrease in PEF variability(P<0.05);Compared with the control group,the total effective rate of treatment in the observation group increased(P<0.05).Conclusion:The treatment of allergic rhinitis with ephedrine Fuzi Asarum Decoction and Guben Tongqiao-Tang can improve the serum factor level and immune function of the patients,with remarkable effect.

Ephedra fuzi Asarum SoupGuben Tongqiao SoupAllergic rhinitisThe immune function

齐斌武、张哲、夏欣欣

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核工业四一七医院中医科,陕西 西安 710600

西安交通大学第一附属医院中医科,陕西 西安 710061

麻黄附子细辛汤 固本通窍汤 过敏性鼻炎 免疫功能

2024

四川中医
四川省中医药学会,四川省中西医结合学会,四川省针灸学会,四川省中医药科学院

四川中医

CSTPCD
影响因子:0.522
ISSN:1000-3649
年,卷(期):2024.42(9)
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