Observation on effects of modified Jinqiao Xiaoying decoction in the treatment of subacute thyroiditis(exogenous heat toxin syndrome)
Objective:To explore the effects of modified Jinqiao Xiaoying decoction on subacute thyroiditis of exogenous heat toxin syndrome.Methods:92patients with subacute thyroiditis of exogenous heat toxin syndrome were randomly divided into control group(46cases)and combined group(46cases).The control group was treated with oral prednisone acetate tablets while the com-bined group was given oral administration of prednisone acetate tablets and modified Jinqiao Xiaoying decoction.The efficacy and im-provement times of symptoms in acute stage,thyroid function indicators[free triiodothyronine(FT3),free thyroxine(FT4),thy-roid stimulating hormone(TSH)],erythrocyte sedimentation rate(ESR)and inflammatory factors[high-sensitivity C-reactive protein(hs-CRP),interleukin-6(IL-6),tumor necrosis factor-α(TNF-α)]before and after treatment were compared be-tween the two groups.The adverse reaction rate and recurrence rate after 3months of follow-up were counted and calculated.Results:The total effective rate of treatment in combined group(91.30％)was significantly higher than that in control group(76.09％)(P＜0.05).Compared with control group,the fever abatement time,pain subsidence time and swelling subsidence time were signifi-cantly shorter in combined group(P＜0.05).The levels of FT3,FT4,ESR,hs-CRP,IL-6and TNF-α in combined group after treatment were significantly reduced(P＜0.05),while the level of TSH was significantly enhanced compared to control group(P＜0.05).There were no statistical differences in the incidence rates of adverse reactions between the two groups during medication(P＞0.05).The recurrence rate in combined group was 2.17％during 3-month follow-up after treatment,which was obviously lower than 13.04％in control group(P＜0.05).Conclusion:Modified Jinqiao Xiaoying decoction has a significant efficacy in treating sub-acute thyroiditis with exogenous heat toxin syndrome,and it can quickly relieve the clinical symptoms,promote the recovery of thy-roid function and ESR,and relieve the body inflammation,with good safety and low recurrence rate.
万方数据
维普
