Efficacy of Fuzheng Qingjie decoction on patients with gouty arthritis of turbidity stasis obstruction type and its influ-ence on TCM syndromes scores and blood uric acid level
Objective:To explore the efficacy of Fuzheng Qingjie decoction in the treatment of patients with gouty arthritis of tur-bidity stasis obstruction type and its influence on TCM syndromes scores and blood uric acid level.Methods:According to the simple randomization grouping method,the patients with turbidity stasis obstruction type of gouty arthritis in our hospital from January 2021to October 2023were divided into observation group(56cases)and control group(56cases).The control group received Qing-zhuo granule treatment,while the observation group was treated with Fuzheng Qingjie decoction on the basis of the control group.The clinical efficacy of the two groups of patients after 1 month of treatment was compared,and the TCM syndromes scores,pain status[Visual Analogue Scale(VAS)],serum indicators and inflammatory indicators were evaluated before treatment and after 1 month of treatment.The adverse reactions during treatment and recurrence status after 1 month of treatment were compared.Results:The to-tal effective rate in observation group after 1 month of treatment was significantly higher than that in control group(P＜0.05).The TCM syndromes scores,VAS score,blood uric acid(UA),erythrocyte sedimentation rate(ESR)and inflammatory indicators in the two groups were significantly reduced after 1 month of treatment than those before treatment,and the above indicators in observa-tion group were lower(P＜0.05).The 24h uric acid excretion(24h UUA)in both groups was significantly enhanced compared with that before treatment,and the observation group had higher 24h UUA than that in control group(P＜0.05).During treatment,there were no significant differences in the incidence rates of adverse reactions between groups(P＞0.05).The recurrence rate in observa-tion group was significantly lower than that in control group after 1 month of treatment(P＜0.05).Conclusion:Fuzheng Qingjie de-coction has a significant efficacy in the treatment of patients with gouty arthritis of turbidity stasis obstruction type.It can effectively improve the TCM syndromes scores,serum indicators and inflammatory indicators,relieve the pain,and reduce the recurrence,and it has good safety.
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