Correlation between TCM syndrome differentiation and serum IL-17,hs-CRP,NT-proBNP and left heart function in patients with chronic heart failure complicated with atrial fibrillation
Objective:To investigate the expression and relationship of serum IL-17,hs-CRP,NT-proBNP and left heart func-tion in patients with chronic heart failure(CHF)complicated with atrial fibrillation(AF).Methods:A total of 100patients with CHF combined with AF admitted to our hospital from January 2021to December 2023were selected as research objects.TCM syndrome dif-ferentiation of patients with CHF complicated with AF was analyzed.The levels of serum interleukin-17(IL),hypersensitive C-reac-tive protein(hs-CRP),N-terminal precursor brain natriuretic peptide(NT-proBNP),and left ventricular function were compared a-mong different syndrome differentiation types.Results:In 100cases of CHF complicated with AF,Qi deficiency and blood stasis ac-counted for 37.00%,Yang deficiency and blood stasis accounted for 26.00%,qi and Yin deficiency and blood stasis accounted for 23.00%,and heart-kidney Yang deficiency accounted for 14.00%.The serum levels of IL-17,hs-CRP and NT-proBNP in patients with different syndrome differentiation types of CHF combined with AF were compared,and the differences were statistically significant(P＜0.05).The levels of left ventricular end-diastolic diameter(LVDd),left atrial diameter(LAD),end-systolic volume(ESV),and left ventricular ejection fraction(LVEF)were compared among patients with different syndrome differentiation types of congestive heart failure combined with atrial fibrillation,and the observed differences were statistically significant(P＜0.05).Qi-deficiency and blood stasis syndrome and Qi-yin deficiency and blood stasis were common in grade Ⅲ,accounting for 51.35%(19/37)and 69.56%(16/23),respectively.Patients with Yang qi deficiency and blood stasis syndrome were common in gradeⅡ,accounting for 46.15%(12/26).The most common patients with heart-kidney Yang deficiency syndrome were grade Ⅳ,accounting for 57.14%(8/14).There was significant difference in cardiac function grading between different TCM syndromes(P＜0.001).Conclusion:Ser-um IL-17,hs-CRP,NT-proBNP and left ventricular function are indeed related to TCM syndrome differentiation and classification of patients with CHF complicated with AF,and the detection of each index can be used as an auxiliary diagnostic index for TCM syn-drome differentiation and classification of patients with CHF complicated with AF.
万方数据
维普
