Thyroid nodules are a common and frequently occurring condition within the endocrine system.The ancients long rec-ognized that endocrine diseases were closely associated with factors such as geographical location,soil,and water environment.The land of Shu,known for its wet climate,was prone to phlegm and blood stagnation.Consequently,treatments for the Shu region focused on addressing dampness,phlegm,and blood stagnation.Drawing upon the experience of differentiating thyroid nodules in Sichuan province,a treatment strategy for the phlegm-dampness and stasis type of thyroid nodules has been proposed,and the therapeutic ex-perience has been summarized to offer a reference for treating similar conditions.