Influence of Huayu Wendan decoction combined with conventional western medicine therapy on neurological function and limb function in patients with convalescent cerebral infarction of phlegm-stasis blocking collateral type
Objective:To explore the influence of Huayu Wendan decoction combined with conventional western medicine thera-py on neurological function and limb function in patients with convalescent cerebral infarction of phlegm-stasis blocking collateral type.Methods:100patients with convalescent cerebral infarction in our hospital were selected from February 2022to January 2024as the re-search subjects.According to the random number table method,they were classified into control group(50cases)and observation group(50cases).The control group was treated with routine western medicine and rehabilitation training,while the observation group was given Huayu Wendan decoction on the basis of the control group.The TCM syndromes scores,neurological function[National In-stitutes of Health Stroke Scale(NIHSS)],limb function[Fugl-Meyer Assessment(FMA),Berg Balance Scale(BBS)],living ability[Barthel Index(BI)rating scale]and nerve factor indicators[brain-derived neurotrophic factor(BNDF),nerve growth factor(NGF)]were compared before and after treatment.Results:After 2months of treatment,the scores of TCM syndromes and score of NIHSS were declined in the two groups,and the above scores in observation group were lower than those in control group(P＜0.05).The FMA upper limb and lower limb scores,BBS score,BI score and levels of serum BDNF and NGF were risen,and the observation group had higher scores and levels than those in control group(P＜0.05).Conclusion:Huayu Wendan decoction combined with con-ventional western medicine therapy can effectively improve the neurological impairment degree,limb movement and balance function,and then enhance the quality of life in patients with convalescent cerebral infarction of phlegm-stasis blocking collateral type,and its role mechanism may be related to the regulations of serum BDNF and NGF levels.
Cerebral infarctionConvalescentHuayu Wendan decoctionNeurological functionLimb function
万方数据
维普
