四川中医2024,Vol.42Issue(12) :166-168.

逍遥散加减治疗中重度痤疮效果及对患者血清辅助性T细胞1(Th1)/Th2型细胞因子的作用

The effect of modified Xiaoyao San on the treatment of moderate to severe acne and its effect on serum helper T cell 1(Th1)/Th2cytokines in patients

姚荣 胡博 任雪雯 邓宇童 孟醒
四川中医2024,Vol.42Issue(12) :166-168.

逍遥散加减治疗中重度痤疮效果及对患者血清辅助性T细胞1(Th1)/Th2型细胞因子的作用

The effect of modified Xiaoyao San on the treatment of moderate to severe acne and its effect on serum helper T cell 1(Th1)/Th2cytokines in patients

姚荣 1胡博 1任雪雯 1邓宇童 1孟醒1
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作者信息

  • 1. 北京中医药大学东方医院皮肤科,北京 100078
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摘要

目的:探讨逍遥散加减治疗中重度痤疮的具体效果,并分析该治疗方法对患者血清辅助性T细胞 1(Th1)/Th2 型细胞因子所产生的具体作用.方法:选取在我院 2022 年 3 月~2024 年 3 月接受治疗的 70 例中重度痤疮患者作为研究对象,将 70 例患者平均分为两个组,每组 35 例患者,分别命名为对照组及观察组.对照组患者采取脉冲染料激光治疗,在此基础上,对观察组患者实行逍遥散加减治疗方式.经一段时间治疗后,对比两组患者的治疗有效率、治疗前后的痤疮症状评分、血清辅助性T细胞 1(Th1)/Th2 型细胞因子水平及不良反应发生概率.结果:观察组的治疗有效率结果相较于对照组更高;经过不同治疗方式后,观察组的痤疮症状评分更低,明显低于对照组;观察组在治疗后痤疮症状评分均低于对照组;观察组T细胞 1(Th1)/Th2 型细胞因子水平均优于对照组;观察组在治疗后发生不良反应的情况较少,发生概率低于对照组.结论:逍遥散加减治疗中重度痤疮患者具有明显的正向效果,能够有效缓解患者的痤疮症状,同时具有较高的安全性,值得临床应用.

Abstract

Objective:To explore the specific effects of modified Xiaoyao San in the treatment of moderate to severe acne,and analyze the specific effects of this treatment method on the production of serum helper T cell 1(Th1)/Th2cytokines in patients.Method:70patients with moderate to severe acne who received treatment in our hospital from March 2022to March 2024were selected as the research subjects.The 70patients were evenly divided into two groups,with 35patients in each group,named the control group and the observation group,respectively.The control group patients were treated with pulsed dye laser,while the observation group re-ceived modified treatment with Xiaoyao Powder on the basis of the control group treatment plan.After a period of treatment,the specif-ic treatment effects,acne symptom scores before and after treatment,serum levels of Th1/Th2cytokines,and the probability of adverse reactions were compared between the two groups of patients.Result:The treatment effect of the observation group was higher than that of the control group;the observation group had lower acne symptom scores than the control group after treatment;the levels of Th1/Th2cytokines in the observation group were superior to those in the control group;the observation group had fewer adverse reactions af-ter treatment,and the probability of occurrence was lower than that of the control group.Conclusion:Xiaoyao San has a significant positive effect in the treatment of moderate to severe acne patients,effectively alleviating their acne symptoms,and has high safety,which is worthy of clinical application.

关键词

逍遥散加减/中重度痤疮/血清辅助性T细胞

Key words

Xiaoyao San with modifications/Moderate to severe acne/Serum helper T cells

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出版年

2024
四川中医
四川省中医药学会,四川省中西医结合学会,四川省针灸学会,四川省中医药科学院

四川中医

CSTPCD
影响因子:0.522
ISSN:1000-3649
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