基于真空管的无水冷微波消融针的设计
Design of waterless cooling microwave ablation needle based on vacuum tube
李军乐 1杨锦 1钱志余1
作者信息
- 1. 南京航空航天大学 自动化学院,南京 211016
- 折叠
摘要
为减少组织碳化,提高微波消融治疗的有效性,本研究根据现有水冷法的原理,设计了一款基于双层不锈钢真空管的无水冷微波消融针.利用离体猪肝实验,验证了真空管隔热的有效性;根据有限元仿真方法建立了微波消融仿真模型,并通过实验验证,达到了更好的消融效果.仿真和实验结果表明,无水冷真空管微波消融针无消融尾迹;与传统带水冷的消融针相比,在相同剂量下,无水冷真空管可得到更大的消融区域和更小的碳化区域.本研究证明了真空管用于无水冷消融的可行性,可为后续设计微波消融针提供新的思路.
Abstract
In order to reduce tissue carbonization,improve the effectiveness of microwave ablation therapy.Based on the principles of existing water-cooling methods,a waterless cooling microwave ablation needle using a double-layer stainless steel vacuum tube was designed.The effectiveness of vacuum tube insulation was verified through ex vivo pig liver experiments.A microwave ablation simula-tion model was established by using finite element simulation methods,and experimental validation was conducted,resulting in im-proved ablation effectiveness.Simulation and experimental results indicated that the waterless cooling vacuum tube microwave ablation needle did not exhibit ablation residues.Compared to traditional water-cooled ablation needles,it could achieve a larger ablation area and a smaller carbonization area at the same dosage.This research demonstrate the feasibility of using a vacuum tube for waterless cool-ing ablation and provide new insights for the subsequent design of microwave ablation needles.
关键词
微波消融/真空管/无水冷消融针/有限元/仿真Key words
Microwave ablation/Vacuum tube/Waterless cooling microwave ablation needle/Finite element/Simulation引用本文复制引用
基金项目
国家自然科学基金重大科研仪器研制项目(81827803)
国家自然科学基金重大科研仪器研制项目(81727804)
国家自然科学基金指南引导类原创探索计划项目(82151311)
国家自然科学基金(61875085)
国家自然科学基金(11902154)
江苏省重点研发计划(社会发展)项目(BE2020705)
江苏省自然科学基金(BK20190387)
出版年
2024
国家科技期刊平台
NSTL
万方数据