膳食氧化平衡评分与脑卒中风险的相关性:基于NHANES的横断面研究
Association between dietary oxidative balance score and stroke:a cross-sectional study based on NHANES database
符一惠 1曾思涛 1吴宇深 1刘竹韵1
作者信息
- 1. 广东省中医院,广东 广州 510120
- 折叠
摘要
目的 探讨膳食氧化平衡评分(DOBS)与成年人群罹患脑卒中风险的相关性,为脑卒中患者的营养管理提供依据.方法 基于2017-2018年国家健康与营养调查(NHANES)成年人群数据作横断面分析,采用多因素Logistic回归模型分析DOBS与脑卒中风险的相关性,构建限制性立方样条曲线以检验DOBS与脑卒中风险之间是否存在定量关系.结果 共纳入3023例成年参与者,其中发现脑卒中患者124例.研究对象总体DOBS为(35.89±8.06),脑卒中患者DOBS水平低于对照组,组间差异具有统计学意义(t=2.822,P=0.005).多因素Logistic回归结果表明,DOBS升高与脑卒中风险降低独立相关(OR=0.976,95%CI:0.954-0.999,P=0.037).RCS分析结果表明,DOBS与脑卒中风险呈负向线性关系(P非线性=0.402),两者间的剂量-反应关系具有统计学意义(P=0.009).结论 成年人罹患脑卒中风险与DOBS呈负相关,优化膳食结构有利于预防脑卒中.
Abstract
Objective To explore the association between dietary oxidative balance score(DOBS)and the risk of stroke in adults,providing a basis for nutritional management of stroke patients.Methods A cross-sectional analysis was conducted based on the 2017-2018 National Health and Nutrition Examination Survey(NHANES)adult data.A multivariable Logistic regression model was used to analyze the association between DOBS and stroke risk,and a restricted cubic spline curve was constructed to test the quantitative relationship between DOBS and stroke risk.Results A total of 3023 adult participants were included,among whom 124 cases of stroke were identified.The overall DOBS of the study subjects was(35.89±8.06),and the DOBS level of stroke patients was lower than that of the control group,with a statistically significant difference between the groups(t=2.822,P=0.005).Multivariable Logistic regression results indicated that higher DOBS was independently associated with a reduced risk of stroke(OR=0.976,95%CI:0.954-0.999,P=0.037).RCS analysis showed a negative linear relationship between DOBS and stroke risk(Pnonlinear=0.402),and the dose-response relationship between the two was statistically significant(P=0.009).Conclusion There is a negative correlation between the risk of stroke in adults and DOBS.Optimizing dietary structure is beneficial for stroke prevention.
关键词
氧化平衡评分/脑卒中/NHANES/横断面研究Key words
oxidative balance score/stroke/NHANES/cross-sectional study引用本文复制引用
出版年
2025
NETL
NSTL
万方数据