首页|突发性耳聋患者早期激素联合高压氧治疗的临床效果分析

突发性耳聋患者早期激素联合高压氧治疗的临床效果分析

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目的 探究突发性耳聋患者早期激素联合高压氧治疗的临床效果。方法 选取本院自2022年3月-2024年1月收治的突发性耳聋患者90例,采取随机数表法分组,每组各45例,对照组采取早期激素治疗,观察组在其基础上增加高压氧治疗,对比两组疗效、治疗前后听阈水平及凝血功能指标,同时对比两组不良反应。结果 观察组与对照组相比,临床总有效率较高,差异有统计学意义(P<0。05)。观察组治疗后与对照组治疗后相比,500Hz、1000Hz、2000Hz的听阈水平较低,差异有统计学意义(P<0。05)。观察组治疗后与对照组治疗后相比,PT值较高、APTT值较高、TT值较高、FIB值较低,差异有统计学意义(P<0。05)。两组不良反应比较,差异无统计学意义(P>0。05)。结论 突发性耳聋患者早期激素联合高压氧治疗的临床效果显著,患者的听阈水平及凝血功能指标均得到了明显的改善,且治疗期间无明显不良反应,安全性有保证。
Clinical effectiveness of early hormone therapy combined with hyperbaric oxygen therapy in patients with sudden sensorineural hearing loss
Objective To investigate and analyze the clinical effects of early hormone therapy combined with hyperbaric oxygen therapy in patients with sudden sensorineural hearing loss(SSNHL).Methods A total of 90 patients with SSNHL,admitted to our hospital from March 2022 to January 2024,were selected and randomly divided into two groups,each with 45 patients.The control group received early hormone therapy,while the observation group received hyperbaric oxygen therapy in addition to hormone therapy.The efficacy,hearing thresholds before and after treatment,coagulation function indicators,and adverse reactions were compared between the two groups.Results The clinical total effective rate in the observation group was significantly higher than that in the control group(P<0.05).After treatment,the hearing thresholds at 500Hz,1000Hz,and 2000Hz in the observation group were lower compared to those in the control group(P<0.05);the PT,APTT,and TT values in the observation group were higher,and the FIB value was lower compared to those in the control group(P<0.05).There were no significant differences in the incidence of adverse reactions between the two groups(P>0.05).Conclusion Early hormone therapy combined with hyperbaric oxygen therapy demonstrates significant clinical efficacy in patients with sudden sensorineural hearing loss.The treatment improves hearing thresholds and coagulation function indicators,and there are no significant adverse reactions,indicating good safety.

Sudden sensorineural hearing lossHormoneHyperbaric oxygenHearing thresholdCoagulation function indicatorsAdverse reactions

刘鹤、孙中武、马亮

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北京航天总医院,北京 100076

突发性耳聋 激素 高压氧 听阈水平 凝血功能指标 不良反应

2025

首都食品与医药
《首都医药》杂志社

首都食品与医药

影响因子:0.389
ISSN:1005-8257
年,卷(期):2025.32(1)