首页|翼状胬肉切除联合自体结膜瓣移植治疗对不同大小翼状胬肉术前术后眼表修复效果的临床比较分析

翼状胬肉切除联合自体结膜瓣移植治疗对不同大小翼状胬肉术前术后眼表修复效果的临床比较分析

扫码查看
目的 研究不同大小翼状胬肉患者通过翼状胬肉切除联合自体结膜瓣移植术治疗后对其眼表修复效果的影响。方法 选择我院在2021年3月-2024年2月期间收治的80例翼状胬肉患者,按照随机数表法分组,对照组(n=40)实施单纯翼状胬肉切除术治疗,观察组(n=40)在对照组基础上,联合自体角膜缘干细胞移植术治疗,对比两组患者治疗前后泪膜破裂时间(BUT)、角膜屈光度、视力水平(UCVA)、泪液分泌试验(SIT)、角膜荧光素染色(FL)评分、眼表疾病指数(OSDI)评分;术后并发症发生率;术后恢复时间(角膜上皮愈合时间、不适感持续时间、视力好转时间、住院时间);眼表修复有效率。结果 治疗前,两组患者的BUT、角膜屈光度、UCVA、SIT、FL评分、OSDI评分对比,差异不显著(P>0。05),治疗后,观察组患者的上述指标均优于对照组(P<0。05);观察组患者术后并发症发生率和对照组对比,差异不显著(P>0。05);观察组患者的角膜上皮愈合时间、不适感持续时间、视力好转时间、住院时间少于对照组(P<0。05);观察组眼表修复总有效率高于对照组(P<0。05)。结论 对于不同大小翼状胬肉患者实施翼状胬肉切除术联合自体结膜瓣移植术进行治疗,可提升其眼表修复效果,安全性良好,促进患者术后恢复,值得推广。
Clinical comparative analysis of the effect of pterygium excision combined with autologous conjunctival flap transplantation on ocular surface repair of different sizes of pterygium before and after surgery
Objective To study the effect of pterygium excision combined with conjunctival autograft transplantation on ocular surface repair in patients with different sizes of pterygium.Methods 80 patients with pterygium treated in our hospital from March 2021 to February 2024 were randomly divided into two groups.The control group(n=40)was treated with simple pterygium excision,and the observation group(n=40)was treated with autologous limbal stem cell transplantation on the basis of the control group.Compare the tear film rupture time(BUT),corneal refractive power,visual acuity level(UCVA),tear secretion test(SIT),corneal fluorescein staining score(FL),and ocular surface disease index score(OSDI)between two groups of patients before and after treatment;incidence of postoperative complications;postoperative recovery time(corneal epithelial healing time,discomfort duration,vision improvement time,hospitalization time);the ocular surface repair is effective.Results Before treatment,the BUT,corneal diopter,UCVA,SIT,FL and OSDI scores of the two groups were compared(P>0.05).After treatment,the above indexes of the patients in the observation group were better than those in the control group(P<0.05).The incidence of postoperative complications in the observation group was compared with that in the control group(P>0.05).The healing time of corneal epithelium,discomfort duration,vision improvement time and hospitalization time in the observation group were shorter than those in the control group(P<0.05).The effective rate of ocular surface repair in the observation group was higher than that in the control group(P<0.05).Conclusion Pterygium excision combined with conjunctival autograft transplantation can improve the effect of ocular surface repair for patients with different sizes of pterygium,which is safe and promotes the postoperative recovery of patients,and is worth popularizing.

pterygium excision surgeryAutologous conjunctival flap transplantationPterygiumEye surface repair effectIncidence of complications

张雪梅

展开 >

湖北省第三人民医院,湖北 武汉 430200

翼状胬肉切除术 自体结膜瓣移植术 翼状胬肉 眼表修复效果 并发症发生率

2025

首都食品与医药
《首都医药》杂志社

首都食品与医药

影响因子:0.389
ISSN:1005-8257
年,卷(期):2025.32(1)