Clinical efficacy of bioinformatics infrared liver disease therapeutic instrument combined with propofol tenofovir fumarate in patients with acute and chronic liver failure caused by hepatitis B virus
Objective To investigate the clinical efficacy of a bioinformatics infrared liver disease treatment device combined with propafenone fumarate in patients with HBV induced acute and chronic liver failure.Methods 120 patients with acute and chronic liver failure caused by hepatitis B virus who were admitted to Tianjin Third Central Hospital from July 2022 to July 2023 were selected and divided into control group and observation group by lot drawing(60 cases in each group).The control group was given propafenone fumarate,while the observation group was given a bioinformatics infrared liver disease treatment device on this basis.The biochemical indexes related to liver function,replication level of hepatitis B virus deoxyribonucleic acid(HBV DNA),peripheral blood cell count,and negative rate of hepatitis B E antigen(HBeAg)were compared between the two groups.Results After treatment,the total bilirubin(TBIL),alanine aminotransferase(ALT),and international normalized ratio(INR)in the observation group were lower than those in the control group,while albumin(ALB)was higher than that in the control group(P＜0.05).After treatment,the white blood cell count(WBC)and neutrophil percentage(NEU)in the observation group were lower than those in the control group,while the hemoglobin concentration(HGB)and platelet count(PLT)were higher than those in the control group(P＜0.05).After treatment,the HBV DNA replication level in the observation group was lower than that in the control group,and the HBeAg conversion rate was 66.67%,which was higher than 46.67%in the control group(P＜0.05).Conclusion The use of propafenone fumarate and bioinformatics infrared liver disease treatment device in patients with acute and chronic liver failure caused by HBV can improve liver function and reduce HBV DNA replication levels.The clinical efficacy is significant and worthy of clinical promotion.
Hepatitis B virusAcute and chronic liver failurePropenovir fumarate
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