Study on the anaesthetic effect of dexmedetomidine compounded with nalbuphine for intrathecal anaesthesia on patients undergoing lower limb fracture surgery and its effect on cognitive functions
Objective To investigate the anaesthetic effect of dexmedetomidine compounded with nalbuphine for intrathecal anaesthesia on patients undergoing lower limb fracture surgery and its influence on postoperative cognitive function.Methods 128 patients with lower limb fracture who underwent surgical treatment in our hospital from January 2023 to July 2024 were selected and grouped into 64 cases in each group using random number table method.The control group received nalbuphine anaesthesia,and the exploratory group received dexmedetomidine combined with nalbuphine anaesthesia.The anaesthetic effects of the two groups were compared.Results At T0,there was no difference in the comparison of vital sign levels between the two groups(P＞0.05).And at T1,T2 and T3,the heart rate,oxygen saturation and blood pressure levels of the exploratory group were overall smoother compared to the control group(P＜0.05).Postoperatively,the cognitive function recovery in the exploratory group was better than that in the control group(P＜0.05).Conclusion Dexmedetomidine combined with nalbuphine for intrathecal anaesthesia can provide more stable control of vital signs in lower limb fracture surgery and better recovery of cognitive function after surgery,making it a safe and effective anaesthetic method.
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