Under the guidance of pharmacists,administering liver protective drugs to prevent liver injury caused by anti-tumor drugs and analyzing the rationality of medication use
Objective To evaluate the effectiveness of liver protective drugs administered under the guidance of pharmacists in preventing liver injury caused by anti-tumor drugs and their impact on the rationality of medication.Methods A total of 74 patients who received anti-tumor drug treatment at Zhongshan People's Hospital from January 2023 to January 2024 were included in the study.They were randomly divided into a control group(37 patients were included,and liver protective drugs were used without the guidance of a pharmacist)and an observation group(37 patients were included,and liver protective drugs were given under the guidance of a pharmacist).The incidence of drug-induced liver injury(DILI)and irrational drug use among the groups were evaluated.Results①Compared with the control group(27.03%),the incidence of DILI in the observation group(5.41%)was lower,P＜0.05;②Compared with the control group(10.81%),the incidence of irrational drug use in the observation group(0.00%)was lower,P＜0.05.Conclusion Under the guidance of pharmacists,administering liver protective drugs to patients receiving anti-tumor drug treatment can improve the rationality of liver protective drug use,effectively prevent liver injury,and have clinical reference significance.
pharmacistGuidanceLiver protective drugsAntitumor drugsLiver injuryReasonability of medication
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