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抗菌药物累积强度法点评结合处方前置审核对抗菌药物用药不合理的预防效果

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目的 探讨抗菌药物累积强度法点评结合处方前置审核对抗菌药物用药不合理的预防效果。方法 选取湛江市第二中医医院2022年4月-2024年3月住院抗菌药物医嘱1135份,其中将2022年4月-2023年3月未经抗菌药物累积强度法点评结合处方前置审核的住院抗菌药物医嘱547份设为对照组,将2023年4月-2024年3月经抗菌药物累积强度法点评结合处方前置审核的抗菌药物医嘱588份设为研究组;对比两组抗菌药物医嘱不合格率及抗菌药物医嘱不合理原因。结果 研究组抗菌药物医嘱不合格率均较对照组低,差异有统计学意义(P<0。05);研究组药物剂量、给药频率、感染证据不足、重复用药不合格发生率均较对照组低,差异有统计学意义(P<0。05)。结论 抗菌药物累积强度法点评结合处方前置审核可预防抗菌药物用药不合理,降低药物医嘱不合格率,未来可作为抗菌药物处方管理重要方案。
Evaluation of antibacterial drug accumulation intensity method combined with prescription pre review to prevent unreasonable antibacterial drug use
Objective To explore the preventive effect of the cumulative intensity method of antibiotics combined with prescription pre review on the unreasonable use of antibiotics.Methods A total of 1135 inpatient antimicrobial medication orders were selected from the Second Traditional Chinese Medicine Hospital of Zhanjiang City from April 2022 to March 2024.Among them,547 inpatient antimicrobial medication orders from April 2022 to March 2023 without antimicrobial cumulative intensity method evaluation combined with prescription pre review were set as the control group,and 588 antimicrobial medication orders from April 2023 to March 2024 with antimicrobial cumulative intensity method evaluation combined with prescription pre review were set as the study group;compare the unqualified rate of antimicrobial medication orders and the reasons for unreasonable antimicrobial medication orders between two groups.Results The unqualified rate of antimicrobial medication orders in the study group was lower than that in the control group,and the difference was statistically significant(P<0.05);the drug dosage,administration frequency,insufficient evidence of infection,and the incidence of repeated administration failure in the study group were all lower than those in the control group,and the differences were statistically significant(P<0.05).Conclusion The combination of cumulative intensity evaluation of antibiotics and pre prescription review can prevent unreasonable use of antibiotics and reduce the rate of medication non-compliance.It can be an important plan for antibiotic prescription management in the future.

Antibacterial drugsAntibacterial drug accumulation intensity methodPrescription pre reviewPrescription reviewPreventive effect

汤志华、袁世新、刘恒、李颜屏、王毓敏

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广东省湛江市第二中医医院,广东 湛江 524000

抗菌药物 抗菌药物累积强度法 处方前置审核 处方点评 预防效果

2025

首都食品与医药
《首都医药》杂志社

首都食品与医药

影响因子:0.389
ISSN:1005-8257
年,卷(期):2025.32(1)