Study on the correlation between TCM syndromes and clinicopathological features of endometrial carcinoma
Objective To explore the correlation between clinicopathological features of endometrial carcinoma and TCM syndrome types.Methods Seventy cases of endometrial cancer patients treated in our hospital from April 2021 to April 2023 were selected as research objects.TCM syndrome types(dampness-heat type,kidney-yin deficiency type,spleen deficiency liver-depression type and dampness-toxin congestion type)were determined according to the symptoms of the patients.Meanwhile,clinicpathological characteristics of the patients were analyzed.Spearman correlation was used to analyze the correlation between clinicopathological features and TCM syndrome types.Results The proportion of Traditional Chinese Medicine syndrome types for 70 patients with endometrial cancer,including damp heat descending type,kidney yin deficiency type,spleen deficiency and liver depression type,and dampness toxin stasis type,were 21.43%,44.29%,15.71%,and 18.57%,respectively.Among them,the proportion of patients with muscle layer infiltration depth＜1/2 and≥1/2 were 64.29%and 35.71%,respectively;the proportions of patients with histological grades G1,G2,and G3 were 68.57%,17.14%,and 14.29%,respectively;the proportion of patients in stages I,II,and III was 70.00%,22.86%,and 7.14%,respectively;the proportion of patients with pathological types of endometrioid adenocarcinoma and non endometrioid adenocarcinoma is 90.00%and 10.00%,respectively.Spearman's results showed that there was a significant positive correlation(P＜0.05)between the depth of muscle infiltration and the damp heat descending type(r=0.346,P＜0.001),kidney yin deficiency type(r=0.582,P＜0.001),spleen deficiency and liver depression type(r=0.927,P＜0.001),and dampness toxin stasis type(r=0.559,P＜0.001),while there was no correlation(P＞0.05)between pathological types and the four Traditional Chinese Medicine syndrome types.Conclusion The TCM syndrome type of endometrial carcinoma is related to the depth of muscle infiltration,histological grade and stage.TCM syndrome type can be used as an indicator to evaluate the prognosis of patients,and the role of TCM in the treatment of endometrial carcinoma can be better played.
NETL
NSTL
万方数据
