Nanocarriers such as liposomes,polymer nanoparticles,and polymer micelles are research hotspots for drug delivery in recent years,but they are easily recognized and cleared by the human immune system after administration.Cell carrying technology can prolong the circulation of nanocarriers in vivo.Red blood cells,as endogenous cells,have the ad-vantages of abundant sources,high biocompatibility and safety of biological elimination mechanism,thus promoting the de-velopment of red blood cell-nanocarrier composite systems.Based on this,this paper reviewed the research progress of sev-eral types of red blood cell-nanocarrier drug delivery systems according to the different construction methods of red blood cells and nanocarriers.
关键词
红细胞/纳米载体/红细胞膜/递药系统
Key words
Red blood cell/Nanocarrier/Erythrocyte membrane/Drug deliver system